Tumor abnormality-oriented nanomedicine design

Q Zhou, J Xiang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

Multifunctional biomolecule nanostructures for cancer therapy

J Wang, Y Li, G Nie - Nature Reviews Materials, 2021 - nature.com
Biomolecule-based nanostructures are inherently multifunctional and harbour diverse
biological activities, which can be explored for cancer nanomedicine. The supramolecular …

State-of-the-art advances in nanocomposite and bio-nanocomposite polymeric materials: A comprehensive review

AH Anwer, A Ahtesham, M Shoeb, F Mashkoor… - Advances in Colloid and …, 2023 - Elsevier
The modern eco-friendly materials used in research and innovation today consist of
nanocomposites and bio-nanocomposite polymers. Their unique composite properties make …

Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches

K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …

Nanostructured particles assembled from natural building blocks for advanced therapies

Y Ju, H Liao, JJ Richardson, J Guo… - Chemical Society …, 2022 - pubs.rsc.org
Advanced treatments based on immune system manipulation, gene transcription and
regulation, specific organ and cell targeting, and/or photon energy conversion have …

Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranostics

W Tang, W Fan, J Lau, L Deng, Z Shen… - Chemical Society …, 2019 - pubs.rsc.org
Brain cancer, especially the most common type of glioblastoma, is highly invasive and
known as one of the most devastating and deadly neoplasms. Despite surgical and medical …

Harnessing albumin as a carrier for cancer therapies

EN Hoogenboezem, CL Duvall - Advanced drug delivery reviews, 2018 - Elsevier
Serum albumin, a natural ligand carrier that is highly concentrated and long-circulating in
the blood, has shown remarkable promise as a carrier for anti-cancer agents. Albumin is …

Biopolymer based nanomaterials in drug delivery systems: A review

J Jacob, JT Haponiuk, S Thomas, S Gopi - Materials today chemistry, 2018 - Elsevier
Drug delivery systems (DDS) are used to achieve a higher therapeutic effects of a
pharmaceutical drug or natural compound in a specific diseased site with minimal …

Applications of surface modification technologies in nanomedicine for deep tumor penetration

Z Li, X Shan, Z Chen, N Gao, W Zeng… - Advanced …, 2021 - Wiley Online Library
The impermeable barrier of solid tumors due to the complexity of their components limits the
treatment effect of nanomedicine and hinders its clinical translation. Several methods are …

Systemic delivery of an adjuvant CXCR4–CXCL12 signaling inhibitor encapsulated in synthetic protein nanoparticles for glioma immunotherapy

MS Alghamri, K Banerjee, AA Mujeeb, A Mauser… - ACS …, 2022 - ACS Publications
Glioblastoma (GBM) is an aggressive primary brain cancer, with a 5 year survival of∼ 5%.
Challenges that hamper GBM therapeutic efficacy include (i) tumor heterogeneity,(ii) …