Glucocorticoids (GCs) are a central component of multi-drug treatment protocols against T
and B acute lymphoblastic leukemia (ALL), which are used intensively during the remission …

Serum and glucocorticoid-inducible kinase 1 (SGK1) is an AGC kinase that has been
reported to be involved in a variety of physiological and pathological processes. Recent …

Endometrium is the mucosal lining of the uterus which expressed a cyclic process of
proliferation, secretion and scaling under the control of hormones secreted by the ovary, and …

The ubiquitin pathway regulates the function of many proteins and controls cellular protein
homeostasis. In recent years, it has attracted great interest in neurodevelopmental and …

The endoplasmic reticulum (ER) is the major intracellular calcium (Ca2+) storage
compartment in eukaryotic cells. In most instances, the mobilization of Ca2+ from this store is …

Being the largest the Ca2+ store in mammalian cells, endoplasmic reticulum (ER)-mediated
Ca2+ signalling often involves both Ca2+ release via inositol 1, 4, 5-trisphosphate receptors …

Reduction oxidation (REDOX) reaction is crucial in life activities, and its dynamic balance is
regulated by ROS. Reactive oxygen species (ROS) is associated with a variety of metabolic …

Located at the level of the endoplasmic reticulum (ER) membrane, stromal interacting
molecule 1 (STIM1) undergoes a complex conformational rearrangement after depletion of …

Abstract Store-operated Ca 2+ entry (SOCE) contributes to Ca 2+ refilling of endoplasmic
reticulum (ER), but also provides Ca 2+ influx involved in physiological and pathological …

KDM2B, a histone lysine demethylase, is expressed in a plethora of cancers. Earlier studies
from our group, have showcased that overexpression of KDM2B in the human prostate …