Unifying approaches from statistical genetics and phylogenetics for mapping phenotypes in structured populations
In both statistical genetics and phylogenetics, a major goal is to identify correlations between
genetic loci or other aspects of the phenotype or environment and a focal trait. In these 2 …
genetic loci or other aspects of the phenotype or environment and a focal trait. In these 2 …
[HTML][HTML] Revealing polygenic pleiotropy using genetic risk scores for asthma
In this study we examined how genetic risk for asthma associates with different features of
the disease and with other medical conditions and traits. Using summary statistics from two …
the disease and with other medical conditions and traits. Using summary statistics from two …
Bayesian approach to assessing population differences in genetic risk of disease with application to prostate cancer
IR Timmins, PRACTICAL Consortium… - Plos Genetics, 2024 - journals.plos.org
Population differences in risk of disease are common, but the potential genetic basis for
these differences is not well understood. A standard approach is to compare genetic risk …
these differences is not well understood. A standard approach is to compare genetic risk …
Genetic similarity between relatives provides evidence on the presence and history of assortative mating
HF Sunde, NH Eftedal, R Cheesman… - Nature …, 2024 - nature.com
Assortative mating–the non-random mating of individuals with similar traits–is known to
increase trait-specific genetic variance and genetic similarity between relatives. However …
increase trait-specific genetic variance and genetic similarity between relatives. However …
Reproduction of socioeconomic differences and mental health across generations
HF Sunde - 2024 - duo.uio.no
The premise of this thesis can be summarized in three statements:(1) Socioeconomic
position runs in families;(2) Mental health runs in families; and (3) Mental health and …
position runs in families;(2) Mental health runs in families; and (3) Mental health and …