Both the initiation and the resolution of inflammatory responses are governed by the
sequential activation, migration, and control/suppression of immune cells at the site of injury …

Leprosy is still a considerable health threat in pockets of several low and middle income
countries worldwide where intense transmission is witnessed, and often results in …

Leprosy reactions are acute inflammatory episodes that complicate the course of a
Mycobacterium leprae infection and are the major cause of leprosy-associated pathology …

Intra-household contacts (HCs) of leprosy patients are at increased risk of infection by
Mycobacterium leprae and about∼ 5–10% will develop active disease. A prognostic tool to …

Background: Obesity induces significant changes in lipid mediators, however, the extent to
which these changes persist after weight loss has not been investigated. Subjects/Methods …

Background Diagnosis of paradoxical tuberculosis-associated immune reconstitution
inflammatory syndrome (TB-IRIS) is challenging and new tools are needed for early …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection currently remains
one of the biggest global challenges that can lead to acute respiratory distress syndrome …

To end the decade-long, obstinately stagnant number of new leprosy cases, there is an
urgent need for field-applicable diagnostic tools that detect infection with Mycobacterium …

Mycobacterium leprae, the causative agent of leprosy, is unique amongst human pathogens
in its capacity to produce the virulence factor phenolic glycolipid (PGL)-I. In addition to …

Background The availability of a diagnostic test to detect subclinical leprosy cases is crucial
to interrupt the transmission of M. leprae. In this study we assessed the minimum sensitivity …