Müller glia are the major glial component of the retina. They are one of the last retinal cell
types to be born during development, and they function to maintain retinal homeostasis and …

For centuries, philosophers and scientists have been fascinated by the principles and
implications of regeneration in lower vertebrate species. Two features have made zebrafish …

In humans, various genetic defects or age-related diseases, such as diabetic retinopathies,
glaucoma, and macular degeneration, cause the death of retinal neurons and profound …

Although human epidemiological and genetic studies are essential to elucidate the
aetiology of normal and aberrant ocular development, animal models have provided us with …

Adult zebrafish generate new neurons in the brain and retina throughout life. Growth-related
neurogenesis allows a vigorous regenerative response to damage, and fish can regenerate …

Müller glia function as retinal stem cells in adult zebrafish. In response to loss of retinal
neurons, Müller glia partially dedifferentiate, re-express neuroepithelial markers and re …

Neural stem/progenitor cells (NSCs) maintain the ability of self-renewal and differentiation
and compose the complex nervous system. Wnt signaling is thought to control the balance of …

Retinal dystrophies are a major cause of blindness for which there are currently no curative
treatments. Transplantation of stem cell‐derived neuronal progenitors to replace lost cells …

Müller glia originate from neuroepithelium and are the principal glial cells in the retina.
During retinal development, Müller glia are one of the last cell types to be born. In lower …

This review covers recent advances in understanding the molecular mechanisms controlling
neurogenesis and specification of the developing retina, with a focus on insights obtained …