Skeletal muscle is an important motor organ with multinucleated myofibers as its smallest
cellular units. Myofibers are formed after undergoing cell differentiation, cell–cell fusion …

Skeletal muscle myogenesis represents one of the most intensively and extensively
examined systems of cell differentiation, tissue formation, and regeneration. Muscle …

Cell-surface exposure of phosphatidylserine (PS) is essential for phagocytic clearance and
blood clotting. Although a calcium-activated phospholipid scramblase (CaPLSase) has long …

Background Skeletal muscle development and regeneration depend on cellular fusion of
myogenic progenitors to generate multinucleated myofibers. These progenitors utilize two …

Mammalian cells contain more than a thousand different glycerophospholipid species that
are essential membrane components and signalling molecules, with phosphatidylserine …

Membrane fusion is a crucial mechanism in a wide variety of important events in cell biology
from viral infection to exocytosis. However, despite many efforts and much progress, cell …

Activation of mitochondrial function and heat production in adipose tissue by the
modification of dietary fat is a promising strategy against obesity. However, as an important …

Zebrafish embryos possess two major types of myofibers, the slow and fast fibers, with
distinct patterns of cell fusion. The fast muscle cells can fuse, while the slow muscle cells …

Myogenic fusion, primarily regulated by the Myomaker and Myomixer proteins, is essential
for skeletal muscle development, yet its mechanisms remain poorly understood. This study …

Purpose: Phosphatidylserine exposed on live and motile sperm is necessary for sperm: egg
fusion, and emerging data suggest it is a biomarker for fertilization competent sperm. Men …