Physical exercise is one of the most effective methods to help prevent cardiovascular (CV)
disease and to promote CV health. Aerobic and anaerobic exercises are two types of …

Abstract cGMP controls many cellular functions ranging from growth, viability, and
differentiation to contractility, secretion, and ion transport. The mammalian genome encodes …

The aging heart is characterized by morphological and structural changes that lead to its
functional decline and are associated with diminished ability to meet increased demand …

Heart diseases due to myocardial ischemia, such as myocardial infarction or ischemic heart
failure, are major causes of death in developed countries, and their number is unfortunately …

Cardiovascular diseases (CVDs) are the major causes of death in the western world. The
incidence of cardiovascular disease as well as the rate of cardiovascular mortality and …

As a family of hormones with pleiotropic effects, natriuretic peptide (NP) system includes
atrial NP (ANP), B-type NP (BNP), C-type NP (CNP), dendroaspis NP and urodilatin, with NP …

Advances in medical care have led to an increase in the number of octogenarians and even
older patients, forming an important and unique patient subgroup. It is clear that advancing …

C-type natriuretic peptide (CNP) is an autocrine and paracrine mediator released by
endothelial cells, cardiomyocytes and fibroblasts that regulates vital physiological functions …

(BNP), and C-type natriuretic peptide (CNP) are the known members of the mammalian
natriuretic peptide system. The discovery of natriuretic peptides (NPs) dates back to 1981 …

Cardiac scars, often dubbed 'dead tissue', are very much alive, with heterocellular activity
contributing to the maintenance of structural and mechanical integrity following heart injury …