A state-of-the-art review on the recent advances of niosomes as a targeted drug delivery system

S Yasamineh, P Yasamineh, HG Kalajahi… - International journal of …, 2022 - Elsevier
The buildup of nonionic surfactants in the aqueous environment produces niosomes. The
usage of niosomes is becoming increasingly frequent due to their sustainability, low cost of …

Spanlastics a novel nanovesicular carrier: its potential application and emerging trends in therapeutic delivery

MD Ansari, Z Saifi, J Pandit, I Khan, P Solanki… - AAPS …, 2022 - Springer
Nanotechnology-based drug delivery system has played a very crucial role in overpowering
the tasks allied with the conventional dosage form. Spanlastics, an elastic nanovesicle with …

Electrochemically Mediated Carboxylative Cyclization of Allylic/Homoallylic Amines with CO2 at Ambient Pressure

YZ Pan, Q Xia, JX Zhu, YC Wang, Y Liang… - Organic …, 2022 - ACS Publications
CO2 is an important C1 resource. We report a method for the synthesis of pharmacologically
active 2-oxazolidinones by reacting CO2 with allylic amines. As opposed to previous …

Spanlastics as a potential approach for enhancing the nose-to-brain delivery of piperine: In vitro prospect and in vivo therapeutic efficacy for the management of …

I Gupta, SN Adin, MA Rashid, Y Alhamhoom, M Aqil… - Pharmaceutics, 2023 - mdpi.com
The present study delineates the preparation of piperine-loaded spanlastics (PIP-SPL) to
improve piperine (PIP) solubility, bioavailability, and permeation through nasal mucosa for …

Glycerospanlastics: State-of-the-art two-in-one nano-vesicles for boosting ear drug delivery in otitis media treatment

M Magdy, E Elmowafy, M Elassal, RAH Ishak - International Journal of …, 2023 - Elsevier
The purpose of this research was to design innovative nanovesicles for ototopical
conveyance of triamcinolone acetonide (TA) for otitis media (OM) treatment via incorporating …

Self-assembling lecithin-based mixed polymeric micelles for nose to brain delivery of clozapine: In-vivo assessment of drug efficacy via radiobiological evaluation

FM Elsharkawy, MM Amin… - International Journal …, 2023 - Taylor & Francis
Purpose The research objective is to design intranasal brain targeted CLZ loaded lecithin
based polymeric micelles (CLZ-LbPM) aiming to improve central systemic CLZ …

Sonophoresis-assisted transdermal delivery of antimigraine-loaded nanolipomers: Radio-tracking, histopathological assessment and in-vivo biodistribution study

MA Tawfik, MM Eltaweel, MM Farag… - International Journal of …, 2023 - Elsevier
Migraine is a disabling neurovascular polygenic disorder affecting life quality with escorted
socioeconomic encumbrances. Herein, we investigated the consolidated amalgamation of …

Nanoparticles of a pyrazolo-pyridazine derivative as potential EGFR and CDK-2 inhibitors: design, structure determination, anticancer evaluation and in silico studies

HE Hashem, AEGE Amr, AA Almehizia, AM Naglah… - Molecules, 2023 - mdpi.com
The strategic planning of this study is based upon using the nanoformulation method to
prepare nanoparticles 4-SLNs and 4-LPHNPs of the previously prepared 4, 5-diphenyl-1 H …

Thin film hydration versus modified spraying technique to fabricate intranasal spanlastic nanovesicles for rasagiline mesylate brain delivery: Characterization …

MM Ali, RA Shoukri, C Yousry - Drug Delivery and Translational Research, 2023 - Springer
Rasagiline mesylate (RM) is a monoamine oxidase inhibitor that is commonly used to
alleviate the symptoms of Parkinson's disease. However, it suffers from low oral …

Fluidized spanlastics for intranasal brain delivery of lacosamide aiming to control Status Epilepticus: Design, Characterization, Ex-vivo permeation, Radioiodination …

ME Sayyed, S Hatem - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
Status Epilepticus (SE) is a neurological condition characterized by anomalous brain
activity, causing repetitive seizures lasting for more than 5 min or periods of unusual …