Association of genetic polymorphisms of CYP2E1, NAT2, GST and SLCO1B1 with the risk of anti-tuberculosis drug-induced liver injury: a systematic review and meta …

S Yang, SJ Hwang, JY Park, EK Chung, JI Lee - BMJ open, 2019 - bmjopen.bmj.com
Objectives The objective of this study was to investigate the association between genetic
polymorphisms of N-acetyltransferase 2 (NAT2), cytochrome P450 2E1 (CYP2E1) …

Association of GST polymorphism with adverse drug reactions: an analysis across multiple drug categories

S Ettoury, S Louati, I Saad, K Bentayebi… - Expert Opinion on …, 2025 - Taylor & Francis
ABSTRACT Introduction Adverse drug reactions (ADRs) pose a significant challenge in
clinical practice, impacting patient safety and treatment outcomes. Genetic variations in drug …

Genetic profiles to identify talents in elite endurance athletes and professional football players

D Varillas-Delgado, E Morencos, J Gutiérrez-Hellín… - PLoS …, 2022 - journals.plos.org
The genetic profile that is needed to identify talents has been studied extensively in recent
years. The main objective of this investigation was to approach, for the first time, the study of …

Liver-metabolizing genes and their relationship to the performance of elite Spanish male endurance athletes; a prospective transversal study

D Varillas Delgado, JJ Tellería Orriols… - Sports Medicine …, 2019 - Springer
Background The genetic profile that is needed to define an endurance athlete has been
studied during recent years. The main objective of this work is to approach for the first time …

Are genetic variations in glutathione S‐transferases involved in anti‐tuberculosis drug‐induced liver injury? A meta‐analysis

M Zhang, S Wu, J He - Journal of Clinical Pharmacy and …, 2019 - Wiley Online Library
What is known and Objective As a crucial protective role in the detoxifying mechanisms of
drugs, glutathione S‐transferases (GSTs) may affect an individual patient's susceptibility to …

Genetic profiles to identify talents in elite endurance athletes and professional football players

D Varillas, E Morencos, J Gutiérrez-Hellín… - 2022 - digital.csic.es
The genetic profile that is needed to identify talents has been studied extensively in recent
years. The main objective of this investigation was to approach, for the first time, the study of …

[图书][B] Improving the Reporting of Pharmacogenetic Studies to Facilitate Evidence Synthesis: Anti-Tuberculosis Drug-Related Toxicity as an Example

M Chaplin - 2021 - search.proquest.com
Background In pharmacogenetic studies, researchers explore how genetic variants impact
individuals' responses to drugs. Implementation of pharmacogenetic tests in clinical practice …

Association of variants within the GST and other genes with anti-tubercular agents related toxicity: a systematic review and meta-analysis

M Richardson, J Kirkham, K Dwan, DJ Sloan, G Davies… - bioRxiv, 2019 - biorxiv.org
Background Individuals receiving treatment with anti-tuberculosis (TB) drugs may
experience serious side-effects, such as anti-TB drug-induced hepatotoxicity (ATDH) …

Liver-metabolizing genes and their relationship to the performance of elite Spanish male endurance athletes; a prospective transversal study

D Varillas, JJ Tellería, C Martín Saborido - 2019 - digital.csic.es
[Methods]: Genotypic and allelic frequencies were determined in 123 elite endurance
athletes (75 professional road cyclists and 48 endurance elite runners) and 122 male non …

[PDF][PDF] EFECTO PROTECTOR DEL EXTRACTO ACUOSO DE LAS HOJAS DE Peumus boldus “Boldo” EN LA TOXICIDAD HEPÁTICA INDUCIDA POR RIFAMPICINA …

JLO Huamán - 2015 - core.ac.uk
Objetivo: Determinar el efecto protector del extracto acuoso de las hojas de Peumus boldus
“Boldo” en la toxicidad hepática inducida por rifampicina en ratas Holtzman hembra …