Emerging role of exosomes in cancer progression and tumor microenvironment remodeling
Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …
The exosome journey: from biogenesis to uptake and intracellular signalling
S Gurung, D Perocheau, L Touramanidou… - Cell Communication and …, 2021 - Springer
The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
The evolving translational potential of small extracellular vesicles in cancer
Cancer-derived extracellular vesicles (EVs) are regarded as having promising potential to
be used as therapeutics and disease biomarkers. Mechanistically, EVs have been shown to …
be used as therapeutics and disease biomarkers. Mechanistically, EVs have been shown to …
[HTML][HTML] Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications
Y Jia, L Yu, T Ma, W Xu, H Qian, Y Sun, H Shi - Theranostics, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles, especially small extracellular vesicles (sEVs) are now accepted as
important messengers in cell-to-cell communication and as a promising drug delivery …
important messengers in cell-to-cell communication and as a promising drug delivery …
The biology, function, and biomedical applications of exosomes
BACKGROUND All cells, prokaryotes and eukaryotes, release extracellular vesicles (EVs)
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …
Comparative analysis of tangential flow filtration and ultracentrifugation, both combined with subsequent size exclusion chromatography, for the isolation of small …
Small extracellular vesicles (sEVs) provide major promise for advances in cancer
diagnostics, prognostics, and therapeutics, ascribed to their distinctive cargo reflective of …
diagnostics, prognostics, and therapeutics, ascribed to their distinctive cargo reflective of …
Isolation and characterization of exosomes for cancer research
L Zhu, HT Sun, S Wang, SL Huang, Y Zheng… - Journal of hematology & …, 2020 - Springer
Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins,
nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes …
nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes …
[HTML][HTML] The biology, function, and applications of exosomes in cancer
J Liu, L Ren, S Li, W Li, X Zheng, Y Yang, W Fu… - … Pharmaceutica Sinica B, 2021 - Elsevier
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids …
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids …
Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution
Metastatic spread of a cancer to secondary sites is a coordinated, non-random process.
Cancer cell-secreted vesicles, especially exosomes, have recently been implicated in the …
Cancer cell-secreted vesicles, especially exosomes, have recently been implicated in the …
Extracellular vesicle-associated proteins in tissue repair
MT Roefs, JPG Sluijter, P Vader - Trends in cell biology, 2020 - cell.com
The administration of (stem) cell-derived extracellular vesicles (EVs) promotes tissue repair
through management of different inflammatory, proliferative and remodeling processes in …
through management of different inflammatory, proliferative and remodeling processes in …