Skeletal muscle is a crucial tissue for movement, gestural assistance, metabolic
homeostasis, and thermogenesis. It makes up approximately 40% of the total body weight …

With aging and other muscle wasting diseases, men and women undergo similar
pathological changes in skeletal muscle: increased inflammation, enhanced oxidative …

Purpose To provide the evidence-based recommendations on the role of testosterone (T) on
age-related symptoms and signs remains. Methods The Italian Society of Andrology and …

Understanding the factors that contribute to exercise response variation is the first step in
achieving the goal of developing personalized exercise prescriptions. This review discusses …

Frailty is a clinical condition related to changes in metabolism, to sarcopenia, and to decline
in muscle mass and strength, bone mineral density, and physical function with aging. The …

Chronic heart failure (CHF) is frequently associated with the involuntary loss of body weight
and muscle wasting, which can determine the course of the disease and its prognosis. While …

Testosterone (T) has a number of important effects on the cardiovascular system. In men, T
levels begin to decrease after age 40, and this decrease has been associated with an …

Male hypogonadism is defined as low circulating testosterone level associated with signs
and symptoms of testosterone deficiency. Although the bidirectional link between …

Malnutrition results from a reduction of food intake or an alteration of nutrient assimilation
and leads to decreased lean mass. Strong evidence shows that malnutrition associated with …

Since it was first synthesized in 1935, testosterone (T) has been viewed as the mythical
Fountain of Youth, promising rejuvenation, restoring sexual appetites, growing stronger …