In addition to the canonical right-handed double helix, other DNA structures, termed 'non-B
DNA', can form in the genomes across the tree of life. Non-B DNA regulates multiple cellular …

G‐quadruplexes are secondary structures formed in G‐rich sequences in DNA and RNA.
Considerable research over the past three decades has led to in‐depth insight into these …

APOBEC mutagenesis, a major driver of cancer evolution, is known for targeting TpC sites in
DNA. Recently, we showed that APOBEC3A (A3A) targets DNA hairpin loops. Here, we …

G-quadruplexes are noncanonical nucleic acid structures formed from stacked guanine
tetrads. They are frequently used as building blocks and functional elements in fields such …

The quadruplex‐based DNAzyme system is one of the most useful artificial enzymes or
catalysts; their unique properties make them reliable alternatives to proteins for performing …

G-quadruplexes can multimerize under certain conditions, but the sequence requirements of
such structures are not well understood. In this study, we investigated the ability of all …

G-quadruplexes are naturally-occurring structures found in RNAs and DNAs. Regular RNA
G-quadruplexes are highly stable due to stacked planar arrangements connected by short …

For many decades it was thought that information storage and information transfer were the
main functions of nucleic acids. However, artificial evolution experiments have shown that …

Single nucleotide polymorphisms (SNPs) are common genetic variations that are present in
over 1% of the population and can significantly modify the structures of both DNA and RNA …

G‐quadruplexes are noncanonical nucleic acid structures formed by stacked guanosine
tetrads. Despite their functional and structural diversity, a single consensus model is typically …