Advancements in spray drying, part II: From configuration to variegated applications in pharmaceuticals and chemical processing

Z Li, C Sun, A Naeem, Q Li, L Yang, Z Jin… - Drying …, 2024 - Taylor & Francis
Drying plays an important role in the preparation of powders, especially in the
pharmaceutical and chemical industries, as it enhances the stability, solubility, and …

Amorphous solid dispersion to facilitate the delivery of poorly water-soluble drugs: recent advances on novel preparation processes and technology coupling

C Luo, R Li, M Tang, Y Gao, J Zhang… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Amorphous solid dispersion (ASD) technique has recently been used as an
effective formulation strategy to significantly improve the bioavailability of insoluble drugs …

Trans-nasal brain delivery of anti-TB drugs by methyl-β-cyclodextrin microparticles show efficient mycobacterial clearance from central nervous system

K Jadhav, A Jhilta, R Singh, S Sharma, S Negi… - Journal of Controlled …, 2025 - Elsevier
Central nervous system tuberculosis (CNS-TB) is the most severe extra-pulmonary
manifestation of tuberculosis (TB), facing significant challenges due to the limited …

Effective cerebral tuberculosis treatment via nose-to-brain transport of anti-TB drugs using mucoadhesive nano-aggregates

K Jadhav, A Jhilta, R Singh, E Ray, V Kumar, AB Yadav… - Nanoscale, 2024 - pubs.rsc.org
Central nervous system tuberculosis (CNS-TB) is a severe form of extra-pulmonary
tuberculosis with high mortality and morbidity rates. The standard treatment regimen for CNS …

Inhalable chitosan-coated nano-assemblies potentiate niclosamide for targeted abrogation of non-small-cell lung cancer through dual modulation of autophagy and …

E Ray, K Jadhav, M Kadian, G Sharma… - International Journal of …, 2024 - Elsevier
Lung carcinoma, particularly non-small-cell lung cancer (NSCLC), accounts for a significant
portion of cancer-related deaths, with a fatality rate of approximately 19%. Niclosamide …

Development, QbD-based optimisation, in-vivo pharmacokinetics, and ex-vivo evaluation of Eudragit® RS 100 loaded flurbiprofen nanoparticles for oral drug …

S Mandpe, E Kole, V Parate, A Chatterjee… - Journal of …, 2024 - Taylor & Francis
This study aims to develop and evaluate flurbiprofen-loaded polymeric nanoparticles to
achieve sustained drug release, enhancing therapeutic efficacy and minimising dosing …

Revealing the potential of nano spray drying for effective delivery of pharmaceuticals and biologicals

K Jadhav, E Kole, A Abhang, S Rojekar… - Drying …, 2024 - Taylor & Francis
The emergence of nano spray drying has revolutionized conventional spray drying by
offering a simple and streamlined approach to obtaining ultrafine powders in the submicron …

Molecular Mechanisms for Stabilizing Biologics in the Solid State

J Ling, Y Du, WP Wuelfing, N Buist… - Journal of …, 2024 - Elsevier
Protein drugs exhibit challenges of biophysical and biochemical instability due to their
structural complexity and rich dynamics. Solid-state biologics aim to enhance stability by …

Effect of different drying approaches on saltiness perception of partially substituted salt

V Kapoor, M Lakshmanan, R Vijayakumar… - Drying …, 2025 - Taylor & Francis
Excessive dietary intake of sodium leads to an increased risk of hypertension and
cardiovascular diseases and novel strategies to reduce sodium consumption are need of the …