SARS-CoV-2 and filovirus enter cells via the cell surface angiotensin-converting enzyme 2
(ACE2) or the late-endosome Niemann-Pick C1 (NPC1) as a receptor. Here, we screened …

Coronavirus stands for a large family of viruses characterized by protruding spikes
surrounding a lipidic membrane adorned with proteins. The present study explores the …

Glycosylation of the SARS-CoV-2 spike (S) protein represents a key target for viral evolution
because it affects both viral evasion and fitness. Successful variations in the glycan shield …

Abstract Each year, SARS-CoV-2 is infecting an increasingly unprecedented number of
species. In the present article, we combine mammalian phylogeny with the genetic …

The efficiency of virus internalization into target cells is a major determinant of infectivity.
SARS-CoV-2 internalization occurs via S-protein-mediated cell binding followed either by …

Ebola virus (EBOV) is an enveloped virus that must fuse with the host cell membrane in
order to release its genome and initiate infection. This process requires the action of the …