[HTML][HTML] Is melatonin the “next vitamin D”?: a review of emerging science, clinical uses, safety, and dietary supplements

DM Minich, M Henning, C Darley, M Fahoum… - Nutrients, 2022 - mdpi.com
Nutrients | Free Full-Text | Is Melatonin the “Next Vitamin D”?: A Review of
Emerging Science, Clinical Uses, Safety, and Dietary Supplements Next Article in Journal …

Melatonin: A mitochondrial resident with a diverse skill set

RJ Reiter, R Sharma, S Rosales-Corral… - Life Sciences, 2022 - Elsevier
Melatonin is an ancient molecule that originated in bacteria. When these prokaryotes were
phagocytized by early eukaryotes, they eventually developed into mitochondria and …

Melatonin: facts, extrapolations and clinical trials

JA Boutin, DJ Kennaway, R Jockers - Biomolecules, 2023 - mdpi.com
Melatonin is a fascinating molecule that has captured the imagination of many scientists
since its discovery in 1958. In recent times, the focus has changed from investigating its …

Brain washing and neural health: role of age, sleep, and the cerebrospinal fluid melatonin rhythm

RJ Reiter, R Sharma, MS Cucielo, DX Tan… - Cellular and Molecular …, 2023 - Springer
The brain lacks a classic lymphatic drainage system. How it is cleansed of damaged
proteins, cellular debris, and molecular by-products has remained a mystery for decades …

Aging-related ovarian failure and infertility: melatonin to the rescue

RJ Reiter, R Sharma, A Romero, W Manucha, DX Tan… - Antioxidants, 2023 - mdpi.com
Aging has a major detrimental effect on the optimal function of the ovary with changes in this
organ preceding the age-related deterioration in other tissues, with the middle-aged …

Melatonin in ventricular and subarachnoid cerebrospinal fluid: Its function in the neural glymphatic network and biological significance for neurocognitive health

RJ Reiter, R Sharma, S Rosales-Corral… - Biochemical and …, 2022 - Elsevier
The central nervous system (CNS) is endowed with a specialized cerebrospinal fluid
(CSF)/lymph network which removes toxic molecules and metabolic by-products from the …

Melatonin modulates tumor metabolism and mitigates metastasis

RJ Reiter, R Sharma, DX Tan, G Huang… - Expert Review of …, 2023 - Taylor & Francis
Introduction Melatonin, originally isolated from the mammalian pineal gland, was
subsequently identified in many animal cell types and in plants. While melatonin was …

[HTML][HTML] Identification of the function and mechanism of m6A reader IGF2BP2 in Alzheimer's disease

Y Deng, H Zhu, L Xiao, C Liu, YL Liu, W Gao - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Alzheimer's disease, the most common form of dementia in the elderly, is a kind of
neurodegenerative disease. However, its pathogenesis and diagnosis remain unclear. M6A …

Dysfunctional mitochondria in age-related neurodegeneration: Utility of melatonin as an antioxidant treatment

RJ Reiter, RN Sharma, W Manucha… - Ageing research …, 2024 - Elsevier
Mitochondria functionally degrade as neurons age. Degenerative changes cause inefficient
oxidative phosphorylation (OXPHOS) and elevated electron leakage from the electron …

Melatonin: the placental antioxidant and anti-inflammatory

TT Joseph, V Schuch, DJ Hossack… - Frontiers in …, 2024 - frontiersin.org
Melatonin (N-acetyl-5-methoxytryptamine) is an indolamine hormone with many
physiological and biological roles. Melatonin is an antioxidant, anti-inflammatory, free …