Reperfusion therapy in acute ischemic stroke: dawn of a new era?

S Bhaskar, P Stanwell, D Cordato, J Attia, C Levi - BMC neurology, 2018 - Springer
Following the success of recent endovascular trials, endovascular therapy has emerged as
an exciting addition to the arsenal of clinical management of patients with acute ischemic …

Application of transcranial Doppler in cerebrovascular diseases

Y Wan, X Teng, S Li, Y Yang - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Transcranial Doppler (TCD) is a rapid and non-invasive diagnostic technique that can
provide real-time measurements of the relative changes in cerebral blood velocity (CBV) …

Endothelial S1P1 Signaling Counteracts Infarct Expansion in Ischemic Stroke

A Nitzsche, M Poittevin, A Benarab, P Bonnin… - Circulation …, 2021 - Am Heart Assoc
Rationale: Cerebrovascular function is critical for brain health, and endogenous vascular
protective pathways may provide therapeutic targets for neurological disorders. S1P …

High variability in neuronal loss: time is brain, requantified

SM Desai, M Rocha, TG Jovin, AP Jadhav - Stroke, 2019 - Am Heart Assoc
Background and Purpose—In the setting of acute ischemic stroke because of large-vessel
occlusion (LVO) there is progressive loss of brain tissue which occurs in a time-dependent …

The pathophysiology of collateral circulation in acute ischemic stroke

M Mangiardi, A Bonura, G Iaccarino, M Alessiani… - Diagnostics, 2023 - mdpi.com
Cerebral collateral circulation is a network of blood vessels which stabilizes blood flow and
maintains cerebral perfusion whenever the main arteries fail to provide an adequate blood …

Collateral blood flow and ischemic core growth

K Seifert, JJ Heit - Translational Stroke Research, 2023 - Springer
Abstract Treatment of a large vessel occlusion in the acute ischemic stroke setting focuses
on vessel recanalization, and endovascular thrombectomy results in favorable outcomes in …

Associations between collateral status and thrombus characteristics and their impact in anterior circulation stroke

HC Alves, KM Treurniet, BG Dutra, IGH Jansen… - Stroke, 2018 - Am Heart Assoc
Background and Purpose—Thrombus characteristics and collateral score are associated
with functional outcome in patients with acute ischemic stroke. It has been suggested that …

Predicting penumbra salvage and infarct growth in acute ischemic stroke: a multifactor survival game

G Sirimarco, D Strambo, S Nannoni… - Journal of Clinical …, 2023 - mdpi.com
Background. Effective treatment of acute ischemic stroke requires reperfusion of
salvageable tissue. We investigated the predictors of penumbra salvage (PS) and infarct …

Promising cerebral blood flow enhancers in acute ischemic stroke

IJ Biose, J Oremosu, S Bhatnagar, GJ Bix - Translational Stroke Research, 2023 - Springer
Ischemic stroke presents a major global economic and public health burden. Although
recent advances in available endovascular therapies show improved functional outcome, a …

High resolution 7T MR imaging in characterizing culprit intracranial atherosclerotic plaques

R Fakih, A Varon Miller, A Raghuram… - Interventional …, 2022 - journals.sagepub.com
Background Current imaging modalities underestimate the severity of intracranial
atherosclerotic disease (ICAD). High resolution vessel wall imaging (HR-VWI) MRI is a …