The circadian timing system is composed of molecular clocks, which drive 24-h changes in
xenobiotic metabolism and detoxification, cell cycle events, DNA repair, apoptosis, and …

The mammalian circadian system is organized in a hierarchical manner in that a central
pacemaker in the suprachiasmatic nucleus (SCN) of the brain's hypothalamus synchronizes …

Various features, components, and functions of the immune system present daily variations.
Immunocompetent cell counts and cytokine levels present variations according to the time of …

Chronic low‐grade inflammation, in particular increased concentrations of proinflammatory
cytokines such as interleukin (IL)‐6 in the circulation, is observed with increasing age, but it …

Disruption of circadian rhythm may be a risk factor in the development of breast cancer, but
molecular changes in circadian rhythm controlled genes in breast cancer cells are still …

Background Rheumatoid arthritis (RA) and depression are conditions which commonly co-
exist. Recent longitudinal studies now suggest a bidirectional association between these …

Hippocampal plasticity and mnemonic processing exhibit a striking time‐of‐day
dependence and likely implicate a temporally structured replay of memory traces. Molecular …

Circadian rhythm plays an important role in the regulation of digestive system. The human
circadian rhythm is controlled by at least nine circadian genes. The aims of this study are to …

A growing body of knowledge is revealing the critical role of circadian physiology in the
development of specific pathological entities such as cancer. NK cell function participates in …

The circadian clock is a self-sustaining oscillator that has a period of∼ 24 h and controls
many physiological and behavioral systems. This clock can synchronize itself to changing …