The combinatorial chemistry and high throughput screening increases the solubility of poorly
water soluble compounds. The most challenging task in development of a formulation is the …

Tacrolimus is an immunosuppressant agent that suffers from poor and variable
bioavailability. This can be related to limited solubility and dissolution. The main objective of …

The present study was aimed to increase the solubility of the poorly water soluble drug
Telmisartan by using Surface solid dispersion (SSD) made of polymers like Poloxamer 407 …

Aceclofenac is widely prescribed with Febuxostat, the drug of choice in gout management, to
eliminate the risk of gout flare. Though, no attempts have been made till date to combine …

The nonsteroidal anti-inflammatory drug aceclofenac was screened with pharmaceutically
acceptable coformers to discover novel solid forms of improved solubility. First, the X-ray …

The objective of the present work was to enhance the solubility and dissolution rate of the
drug raloxifene HCl (RLX), which is poorly soluble in water. The solubility of RLX was …

This study details the isotherm adsorption properties of cross-linked polymers containing β-
cyclodextrin (β-CD), hereafter referred to as macromolecular imprinted materials (MIMs). The …

Objective: The objective of the present study was to the preparation of a coamorphous
(COAM) system of paracetamol (PA)(Biopharmaceutics Classification System [BCS] Class …

The purpose of this study is to enhance solubility and dissolution rate of poorly water soluble
drug, Different methods are used for solubility enhancement such as particle size reduction …

The aim of the present study was to enhance the physicochemical properties of poorly
aqueous soluble carvedilol (CRV) by preparing its microparticles in presence and/or in …