The role of mitochondrial dynamics in oocyte and early embryo development

RM Yildirim, E Seli - Seminars in Cell & Developmental Biology, 2024 - Elsevier
Mitochondrial dysfunction is widely implicated in various human diseases, through
mechanisms that go beyond mitochondria's well-established role in energy generation …

Metabolic theory of preeclampsia: Implications for maternal cardiovascular health

MM Manoharan, GC Montes… - American Journal …, 2024 - journals.physiology.org
Preeclampsia (PE) is a multisystemic disorder of pregnancy that not only causes perinatal
mortality and morbidity but also has a long-term toll on the maternal and fetal cardiovascular …

Glycolysis: A fork in the path of normal and pathological pregnancy

R Gou, X Zhang - The FASEB Journal, 2023 - Wiley Online Library
Glucose metabolism is vital to the survival of living organisms. Since the discovery of the
Warburg effect in the 1920s, glycolysis has become a major research area in the field of …

Cadmium Associated Preeclampsia: A Systematic Literature Review of Pregnancy and Birth Outcomes

F Sardar, YS Kamsani, F Ramly… - Biological trace element …, 2024 - Springer
Preeclampsia (PE), caused by multiple factors, is one of the most serious complications of
pregnancy. Cadmium (Cd) is a heavy metal environmental pollutant, reproductive toxicant …

The effect of low birth weight as an intrauterine exposure on the early onset of sarcopenia through possible molecular pathways

D Celik, M Campisi, L Cannella… - Journal of Cachexia …, 2024 - Wiley Online Library
Sarcopenia, a musculoskeletal disease characterized by the progressive loss of skeletal
muscle mass, strength, and physical performance, presents significant challenges to global …

Modulation of placental angiogenesis by metformin in a rat model of gestational diabetes

BM Eldakhakhny, FM Ghoneim, MFM Soliman… - Histochemistry and Cell …, 2025 - Springer
Gestational diabetes mellitus (GDM) significantly disrupts placental structure and function,
leading to complications such as intrauterine growth restriction (IUGR) and preeclampsia …

Mitochondrial quality control alterations and placenta-related disorders

Y Wu, M Li, H Ying, Y Gu, Y Zhu, Y Gu… - Frontiers in …, 2024 - frontiersin.org
Mitochondria are ubiquitous in eukaryotic cells. Normal maintenance of function is the
premise and basis for various physiological activities. Mitochondrial dysfunction is …

An integral role of mitochondrial function in the pathophysiology of preeclampsia

H Kobayashi, C Yoshimoto, S Matsubara… - Molecular Biology …, 2024 - Springer
Preeclampsia (PE) is associated with high maternal and perinatal morbidity and mortality.
The development of effective treatment strategies remains a major challenge due to the …

自噬在胎儿生长发育及妊娠并发症中的作用.

吴亚梅, 李濛, 李佳雯, 应豪… - Journal of International …, 2023 - search.ebscohost.com
自噬是一种高度保守的胞内物质清除机制, 具有维持细胞内稳态, 促进代谢循环,
维持能量平衡的作用, 同时也是一个维系细胞生存的自稳定过程. 研究表明自噬在妊娠滋养细胞 …

Effects of exposure to polycyclic aromatic hydrocarbons and heavy metals on placental trophoblasts and childhood inflammation

Y Dai - 2023 - research.rug.nl
Environmental pollution, the introduction of harmful substances into the environment, is one
of our most serious public health issues. The pollutants introduced into the natural …