Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers
S Nooraei, H Bahrulolum, ZS Hoseini… - Journal of …, 2021 - Springer
Virus-like particles (VLPs) are virus-derived structures made up of one or more different
molecules with the ability to self-assemble, mimicking the form and size of a virus particle but …
molecules with the ability to self-assemble, mimicking the form and size of a virus particle but …
Beyond binding: antibody effector functions in infectious diseases
LL Lu, TJ Suscovich, SM Fortune, G Alter - Nature Reviews Immunology, 2018 - nature.com
Antibodies play an essential role in host defence against pathogens by recognizing
microorganisms or infected cells. Although preventing pathogen entry is one potential …
microorganisms or infected cells. Although preventing pathogen entry is one potential …
Broad betacoronavirus neutralization by a stem helix–specific human antibody
The spillovers of betacoronaviruses in humans and the emergence of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) variants highlight the need for broad …
respiratory syndrome coronavirus 2 (SARS-CoV-2) variants highlight the need for broad …
Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms
MA Tortorici, M Beltramello, FA Lempp, D Pinto… - Science, 2020 - science.org
Efficient therapeutic options are needed to control the spread of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) that has caused more than 922,000 fatalities as of …
syndrome coronavirus 2 (SARS-CoV-2) that has caused more than 922,000 fatalities as of …
Interrogation of the microenvironmental landscape in brain tumors reveals disease-specific alterations of immune cells
Brain malignancies encompass a range of primary and metastatic cancers, including low-
grade and high-grade gliomas and brain metastases (BrMs) originating from diverse …
grade and high-grade gliomas and brain metastases (BrMs) originating from diverse …
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2
Summary The SARS-CoV-2 spike (S) glycoprotein contains an immunodominant receptor-
binding domain (RBD) targeted by most neutralizing antibodies (Abs) in COVID-19 patient …
binding domain (RBD) targeted by most neutralizing antibodies (Abs) in COVID-19 patient …
Role of Bruton's tyrosine kinase in B cells and malignancies
S Pal Singh, F Dammeijer, RW Hendriks - Molecular cancer, 2018 - Springer
Bruton's tyrosine kinase (BTK) is a non-receptor kinase that plays a crucial role in oncogenic
signaling that is critical for proliferation and survival of leukemic cells in many B cell …
signaling that is critical for proliferation and survival of leukemic cells in many B cell …
Proinflammatory IgG Fc structures in patients with severe COVID-19
S Chakraborty, J Gonzalez, K Edwards… - Nature …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 infections can cause coronavirus disease
2019 (COVID-19), which manifests with a range of severities from mild illness to life …
2019 (COVID-19), which manifests with a range of severities from mild illness to life …
Single-cell transcriptome analysis highlights a role for neutrophils and inflammatory macrophages in the pathogenesis of severe COVID-19
Cumulative data link cytokine storms with coronavirus disease 2019 (COVID-19) severity.
The precise identification of immune cell subsets in bronchoalveolar lavage (BAL) and their …
The precise identification of immune cell subsets in bronchoalveolar lavage (BAL) and their …
How do red blood cells die?
P Thiagarajan, CJ Parker, JT Prchal - Frontiers in physiology, 2021 - frontiersin.org
Normal human red blood cells have an average life span of about 120 days in the circulation
after which they are engulfed by macrophages. This is an extremely efficient process as …
after which they are engulfed by macrophages. This is an extremely efficient process as …