The S100 protein family is the largest subgroup within the superfamily of proteins carrying
the Ca2+-binding EF-hand motif. Despite their small molecular size and their conserved …

The Receptor for Advanced Glycation Endproducts (RAGE) is a multi-ligand receptor of the
immunoglobulin family. RAGE interacts with structurally different ligands probably through …

Purpose: Oral fluid (saliva) meets the demand for noninvasive, accessible, and highly
efficient diagnostic medium. Recent discovery that a large panel of human RNA can be …

The PR-A and PR-B isoforms of progesterone receptors (PR) have different physiological
functions, and their ratio varies widely in breast cancers. To determine whether the two PR …

Receptor for advanced glycation end-products (RAGE) is a member of the immunoglobulin
superfamily. RAGE binds and mediates cellular responses to a range of DAMPs (damage …

The vast diversity of S100 proteins has demonstrated a multitude of biological correlations
with cell growth, cell differentiation and cell survival in numerous physiological and …

The S100 protein family comprises at least 25 members which, with the exception of S100G,
act as Ca2+-sensor proteins that participate in Ca2+ signal transduction by interacting with …

S100P is a member of the S100 protein family that is expressed in several malignant
neoplasms. Currently the effects of this molecule on cell function are unknown. In the …

Purpose: In the current study, we examined the functional significance and mechanism of
action of S100P in pancreatic cancer cells. Experimental Design: S100P levels were …

DNA hypomethylation is one of the major epigenetic alterations in human cancers. We have
previously shown that genes identified as hypomethylated in pancreatic cancer are …