Molecular radiotherapy (MRT) has demonstrated unique therapeutic advantages in the
treatment of an increasing number of cancers. As with other treatment modalities, there is …

Neuroblastoma is a common malignancy observed in infants and young children. It has a
varied prognosis, ranging from spontaneous regression to aggressive metastatic tumors with …

Purpose To evaluate the effect of disease sites and prior therapy on response and toxicity
after iodine-131-metaiodobenzylguanidine (131I-MIBG) treatment of patients with resistant …

Neuroblastoma, the most common extracranial pediatric solid tumor remains a clinical
enigma with outcomes ranging from cure in> 90% of patients with locoregional tumors with …

The optimal use and effectiveness of 131 I-meta iodobenzylguanidine (131 I-mIBG)
molecular radiotherapy for neuroblastoma remain unclear despite extensive clinical …

Purpose To determine the maximum-tolerated dose (MTD) and toxicity of iodine-131–
metaiodobenzylguanidine (131I-MIBG) with carboplatin, etoposide, melphalan (CEM) and …

The purpose of the EANM Dosimetry Committee Series on “Standard Operational
Procedures for Dosimetry”(SOP) is to provide advice to scientists and clinicians on how to …

Metaiodobenzylguanidine (MIBG) is structurally similar to the neurotransmitter
norepinephrine and specifically targets neuroendocrine cells including some …

Neuroblastoma is the most common extracranial solid tumor in children and arises from
anywhere along the sympathetic nervous system. It is a highly heterogeneous disease with …

Introduction Radionuclide therapy has distinct similarities to, but also profound differences
from external radiotherapy. Review This review discusses techniques and results of …