[HTML][HTML] The role of matrix metalloproteinase-9 in cardiac remodeling and dysfunction and as a possible blood biomarker in heart failure
KE Rodrigues, MHB Pontes, MBS Cantão… - Pharmacological …, 2024 - Elsevier
Heart failure (HF) is the leading cause of morbidity and mortality in cardiovascular diseases,
being responsible for many hospitalizations annually. HF is considered a public health …
being responsible for many hospitalizations annually. HF is considered a public health …
NLRP3 inflammasome activation‐mediated pyroptosis aggravates myocardial ischemia/reperfusion injury in diabetic rats
Z Qiu, S Lei, B Zhao, Y Wu, W Su, M Liu… - Oxidative medicine …, 2017 - Wiley Online Library
The reactive oxygen species‐(ROS‐) induced nod‐like receptor protein‐3 (NLRP3)
inflammasome triggers sterile inflammatory responses and pyroptosis, which is a …
inflammasome triggers sterile inflammatory responses and pyroptosis, which is a …
Redox-mediated signal transduction by cardiovascular Nox NADPH oxidases
RP Brandes, N Weissmann, K Schröder - Journal of molecular and cellular …, 2014 - Elsevier
The only known function of the Nox family of NADPH oxidases is the production of reactive
oxygen species (ROS). Some Nox enzymes show high tissue-specific expression and the …
oxygen species (ROS). Some Nox enzymes show high tissue-specific expression and the …
Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells
D Olagnier, S Peri, C Steel, N van Montfoort… - PLoS …, 2014 - journals.plos.org
Dengue virus (DENV) is a re-emerging arthropod borne flavivirus that infects more than 300
million people worldwide, leading to 50,000 deaths annually. Because dendritic cells (DC) …
million people worldwide, leading to 50,000 deaths annually. Because dendritic cells (DC) …
[HTML][HTML] SIRT1 agonism modulates cardiac NLRP3 inflammasome through pyruvate dehydrogenase during ischemia and reperfusion
Y Han, W Sun, D Ren, J Zhang, Z He, J Fedorova… - Redox biology, 2020 - Elsevier
Nucleotide-binding oligomerization domain-Like Receptor with a Pyrin domain 3 (NLRP3)
inflammasome was emerged as a marker of metabolic dysregulation. We revealed that age …
inflammasome was emerged as a marker of metabolic dysregulation. We revealed that age …
Oxidative stress in granulosa cells contributes to poor oocyte quality and IVF-ET outcomes in women with polycystic ovary syndrome
Q Lai, W Xiang, Q Li, H Zhang, Y Li, G Zhu, C Xiong… - Frontiers of …, 2018 - Springer
The increased levels of intracellular reactive oxygen species (ROS) in granulosa cells (GCs)
may affect the pregnancy results in women with polycystic ovary syndrome (PCOS). In this …
may affect the pregnancy results in women with polycystic ovary syndrome (PCOS). In this …
Diabetes aggravates myocardial ischaemia reperfusion injury via activating Nox2‐related programmed cell death in an AMPK‐dependent manner
C Wang, L Zhu, W Yuan, L Sun, Z Xia… - Journal of cellular …, 2020 - Wiley Online Library
Cardiovascular diseases such as myocardial ischaemia have a high fatality rate in patients
with diabetes. This study was designed to expose the crosstalk between oxidative stress and …
with diabetes. This study was designed to expose the crosstalk between oxidative stress and …
Pristimerin inhibits MMP-9 expression and cell migration through attenuating NOX/ROS-dependent NF-κB activation in rat brain astrocytes challenged with LPS
Purpose Neuroinflammation plays a crucial role in neurodegenerative diseases. Matrix
metalloproteinases (MMPs) are a landmark of neuroinflammation. Lipopolysaccharide (LPS) …
metalloproteinases (MMPs) are a landmark of neuroinflammation. Lipopolysaccharide (LPS) …
Cardiac remodelling following cancer therapy: a review
T Panpan, D Yuchen, S Xianyong, L Meng… - Cardiovascular …, 2022 - Springer
Cardiac remodelling is characterized by abnormal changes in the function and
morphological properties such as diameter, mass, normal diameter of cavities, heart shape …
morphological properties such as diameter, mass, normal diameter of cavities, heart shape …
Tumor necrosis factor-α-induced nuclear factor-kappaB activation in human cardiomyocytes is mediated by NADPH oxidase
KT Moe, K Khairunnisa, NO Yin, J Chin-Dusting… - Journal of physiology …, 2014 - Springer
An elevated level of tumor necrosis factor (TNF)-α is implicated in several cardiovascular
diseases including heart failure. Numerous reports have demonstrated that TNF-α activates …
diseases including heart failure. Numerous reports have demonstrated that TNF-α activates …