[HTML][HTML] The Macrophage–Fibroblast Dipole in the Context of Cardiac Repair and Fibrosis

S Psarras - Biomolecules, 2024 - mdpi.com
Stromal and immune cells and their interactions have gained the attention of cardiology
researchers and clinicians in recent years as their contribution in cardiac repair is …

Targeting macrophage–fibroblast interactions in the failing heart

NG Frangogiannis - Nature Reviews Cardiology, 2024 - nature.com
Macrophage–fibroblast interactions have a central role in cardiac fibrosis. In response to left
ventricular pressure overload, CCR2+ cardiac macrophages acquire a fibrogenic …

[HTML][HTML] Immunological Regulation of Fibrosis During Heart Failure: It Takes Two to Tango

V Kumar, SS Bansal - Biomolecules, 2025 - mdpi.com
Immuno-fibrotic networks and their protein mediators, such as cytokines and chemokines,
have increasingly been appreciated for their critical role in cardiac healing and fibrosis …

Mapping spatially-resolved transcriptomes in systemic sclerosis

Z Li, AR Rigau, W Xie, X Shao, YN Li, AE Matei, H Zou… - bioRxiv, 2025 - biorxiv.org
Systemic sclerosis (SSc) is a prototypical fibrotic disease with high mortality and limited
treatment options. Despite advances in single-cell RNA sequencing (scRNA-seq), the …

Insights into immune cell–fibroblast communication in heart disease

A Flemming - Nature Reviews Immunology, 2024 - nature.com
Insights into immune cell–fibroblast communication in heart disease | Nature Reviews
Immunology Skip to main content Thank you for visiting nature.com. You are using a browser …