Sample preparation of formalin-fixed paraffin-embedded tissue sections for MALDI-mass spectrometry imaging

J Hermann, H Noels, W Theelen, M Lellig… - Analytical and …, 2020 - Springer
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MALDI
MSI) has become a powerful tool with a high potential relevance for the analysis of …

Proteomics and leishmaniasis: potential clinical applications

J Capelli‐Peixoto, SN Mule, FT Tano… - PROTEOMICS …, 2019 - Wiley Online Library
Leishmaniases are diseases caused by protozoan parasites of the genus Leishmania. They
are endemic in 98 countries, affect around 12 million people worldwide and may present …

Proteome imaging: from classic to modern mass spectrometry-based molecular histology

AN Neagu - Advancements of Mass Spectrometry in Biomedical …, 2019 - Springer
In order to overcome the limitations of classic imaging in Histology during the actually era of
multiomics, the multi-color “molecular microscope” by its emerging “molecular pictures” …

Mass spectrometry imaging identifies altered hepatic lipid signatures during experimental Leishmania donovani infection

R Tans, S Dey, NS Dey, JH Cao, PS Paul… - Frontiers in …, 2022 - frontiersin.org
Introduction Spatial analysis of lipids in inflammatory microenvironments is key to
understand the pathogenesis of infectious disease. Granulomatous inflammation is a …

Changes in saliva of dogs with canine leishmaniosis: A proteomic approach

L Franco-Martínez, A Tvarijonaviciute, A Horvatić… - Veterinary …, 2019 - Elsevier
In the present study, a quantitative proteomic approach to study changes in saliva proteins
associated with canine leishmaniosis (CanL) was performed. For this, canine salivary …

Mass spectrometric (MS) analysis of proteins and peptides

M Jayathirtha, EJ Dupree, Z Manzoor… - Current Protein and …, 2021 - ingentaconnect.com
The human genome is sequenced and comprised of~ 30,000 genes, making humans just a
little bit more complicated than worms or flies. However, complexity of humans is given by …

Pharmacokinetics and pharmacodynamics in the treatment of cutaneous leishmaniasis–challenges and opportunities

K Van Bocxlaer, SL Croft - RSC medicinal chemistry, 2021 - pubs.rsc.org
Pharmacological efficacy is obtained when adequate concentrations of a potent drug reach
the target site. In cutaneous leishmaniasis, a heterogeneous disease characterised by a …

MALDI mass spectrometry imaging for microbiology

JE Porter, LM Sanchez - 2021 - books.rsc.org
Microbiology concerns the study of microorganisms. Within the broad field of microbiology,
there are many subcategories and areas of study, which can be divided taxonomically (eg …

[HTML][HTML] MALDI-MSI method for the detection of large biomolecules in plant leaf tissue

LST Carmo, DG Ribeiro, EA Barbosa… - Journal of Plant …, 2021 - plantsciencejournal.com
In this study we describe a method for the detection of biomolecules (in the polypeptide m/z
range) directly from the surface of plant leaves by using Mass Spectrometry Imaging. The …

MALDI Mass Spectrometry Imaging of Neuropeptides

J Hanrieder - 2021 - books.rsc.org
Neuropeptides, including peptide hormones, are key modulators in the brain that represent
the largest class of chemical messengers for cell-to-cell communication. 1–5 Due to the …