Nrf2 and NF-κB are important regulators of the response to oxidative stress and
inflammation in the body. Previous pharmacological and genetic studies have confirmed …

Acute kidney injury (AKI) is a common clinical syndrome that is related to high morbidity and
mortality. Oxidative stress, including the production of reactive oxygen species (ROS) …

Background Kiwifruit is a worldwide appreciated fruit with significant economic and
nutritionally importance. Its industrial processing generates high amount of waste, which …

Background Gentamycin, contrary to its wide range of antimicrobial effects, has a high
potential for nephrotoxicity, and renal injury can have effects on other organs such as the …

Nephropathy can occur following exposure of the kidneys to oxidative stress. Oxidative
stress is the result of reactive oxygen species (ROS) formation due to intracellular …

Clinical application of gentamicin (GM) is well known to be associated with the development
of acute kidney injury (AKI). This study was the first to investigate the possible protective …

Kiwi and pepino fruits are most valuable fruits as they contains substantial amounts of
nutrients and bioactive compounds. These fruits exhibited several health potentials such as …

A highly selective lysosome-targeting NIR fluorescent probe (Lyso-SiR-2S) for HOCl was
constructed based on Si-rhodamine B spirodithiolactone. This probe was very effectively …

Drug-induced nephrotoxicity (DIN) is a major cause of kidney damage and is associated
with high mortality and morbidity, which limits the clinical use of certain therapeutic or …

Gentamicin remains widely used in all age groups despite its well-documented
nephrotoxicity; however, no adjuvant therapies have been established to counteract this …