Epidemiology and outcomes of pediatric multiple organ dysfunction syndrome

RS Watson, SS Crow, ME Hartman… - Pediatric Critical Care …, 2017 - journals.lww.com
Objective: To summarize the epidemiology and outcomes of children with multiple organ
dysfunction syndrome as part of the Eunice Kennedy Shriver National Institute of Child …

The role of DAMPS in burns and hemorrhagic shock immune response: pathophysiology and clinical issues. Review

D Pantalone, C Bergamini, J Martellucci… - International Journal of …, 2021 - mdpi.com
Severe or major burns induce a pathophysiological, immune, and inflammatory response
that can persist for a long time and affect morbidity and mortality. Severe burns are followed …

Detection of circulating Mucorales DNA in critically ill burn patients: preliminary report of a screening strategy for early diagnosis and treatment

M Legrand, M Gits-Muselli, L Boutin… - Clinical Infectious …, 2016 - academic.oup.com
Background. Invasive wound mucormycosis (IWM) is associated with an extremely poor
outcome among critically ill burn patients. We describe the detection of circulating Mucorales …

Threshold age and burn size associated with poor outcomes in the elderly after burn injury

MG Jeschke, R Pinto, SR Costford, S Amini-Nik - Burns, 2016 - Elsevier
Elderly burn care represents a vast challenge. The elderly are one of the most susceptible
populations to burn injuries, but also one of the fastest growing demographics, indicating a …

Health care resource use and costs after hospitalization with multiple organ dysfunction in children

FO Odetola, P Lin, W Ye, KJ Dombkowski… - JAMA Network …, 2025 - jamanetwork.com
Importance Multiple organ dysfunction (MOD) is a leading cause of in-hospital child
mortality. For survivors, posthospitalization health care resource use and costs are unknown …

[HTML][HTML] Management of severe thermal burns in the acute phase in adults and children

M Legrand, D Barraud, I Constant… - … Critical Care & Pain …, 2020 - Elsevier
Objectives To provide recommendations to facilitate the management of severe thermal
burns during the acute phase in adults and children. Design A committee of 20 experts was …

Gastrointestinal dysfunction is associated with mortality in severe burn patients: a 10-year retrospective observational study from South China

QL He, SW Gao, Y Qin, RC Huang, CY Chen… - Military Medical …, 2022 - Springer
Background Data on severe and extensive burns in China are limited, as is data on the
prevalence of a range of related gastrointestinal (GI) disorders [such as stress ulcers …

[HTML][HTML] The effects of major burn related pathophysiological changes on the pharmacokinetics and pharmacodynamics of drug use: An appraisal utilizing antibiotics

AA Udy, JA Roberts, J Lipman, S Blot - Advanced drug delivery reviews, 2018 - Elsevier
Patients suffering major burn injury represent a unique population of critically ill patients.
Widespread skin and tissue damage causes release of systemic inflammatory mediators that …

TNF-α/IL-10 ratio correlates with burn severity and may serve as a risk predictor of increased susceptibility to infections

A Tsurumi, YA Que, CM Ryan, RG Tompkins… - Frontiers in public …, 2016 - frontiersin.org
Severe burn injury renders patients susceptible to multiple infection episodes; however,
identifying specific patient groups at high risk remains challenging. Burn-induced …

Prognostic values of red blood cell distribution width, platelet count, and red cell distribution width-to-platelet ratio for severe burn injury

L Qiu, C Chen, SJ Li, C Wang, F Guo, A Peszel… - Scientific Reports, 2017 - nature.com
Red blood cell distribution width (RDW), platelet count (PLT), and a RDW-to-PLT ratio (RPR)
have been associated with inflammatory activity and adverse outcomes in many diseases …