Abstract The sirtuins (SIRT1–7) are a family of nicotinamide adenine dinucleotide (NAD+)-
dependent deacylases with remarkable abilities to prevent diseases and even reverse …

Extensive research within the last decade has revealed that most chronic illnesses such as
cancer, cardiovascular and pulmonary diseases, neurological diseases, diabetes, and …

В монографии проанализированы основные концепции о природе старения, история
их возникновения и эволюция. Изложены современные представления о …

While ruling out programmed aging, evolutionary theory predicts a quasi-program for aging,
a continuation of the developmental program that is not turned off, is constantly on …

Ageing, which all creatures must encounter, is a challenge to every living organism. In the
human body, it is estimated that cell division and metabolism occurs exuberantly until about …

Introduction 3. Mechanisms of Action 3.1. Regulation of Bcl-2 family members 3.2.
Regulation of cell cycle 3.3. Regulation of MAP kinase 3.4. Generation of Reactive Oxygen …

Aging is an inevitable and multifactorial biological process. Free radicals have been
implicated in aging processes; it is hypothesized that they cause cumulative oxidative …

Based on the data of the literature it can be stated that the original composition of the seeds
essentially changes during germination. The quantity of the protein fractions changes, the …

Human ageing is a fundamental biological process that leads to functional decay, increased
risk for various diseases and, ultimately, death. Some of the basic biological mechanisms …

One of the current problems in medicine research is the development of safe drugs for the
treatment of neurological disorders. Furthermore, there is a close relationship between the …