Background The use of peripheral nerve blocks for anesthesia and postoperative analgesia
has increased significantly in recent years. Adjuvants are frequently added to local …

Background. Dexmedetomidine has been proposed as a perineural local anaesthetic (LA)
adjunct to prolong peripheral nerve block duration; however, results from our previous meta …

Background Brachial plexus nerve blocks (BPBs) have analgesic and opioid sparing
benefits for upper extremity surgery. Single-injection techniques are limited by the …

BACKGROUND: Interscalene block (ISB) can provide pain relief after shoulder surgery, but
a reliable quantification of its analgesic benefits is lacking. This meta-analysis examines the …

Background Interscalene brachial plexus block (ISB) provides excellent, but time-limited
analgesia. Dexamethasone added to local anaesthetics prolongs the duration of a single …

Background: Perineural and IV dexmedetomidine have each been suggested to prolong the
duration of analgesia when administered in conjunction with peripheral nerve blocks. In the …

We systematically reviewed the safety and efficacy of perineural dexamethasone as an
adjunct for peripheral nerve blockade in 29 controlled trials of 1695 participants. We …

Moderate‐to‐severe postoperative pain persists for longer than the duration of single‐shot
peripheral nerve blocks and hence continues to be a problem even with the routine use of …

Background and Objectives Perineural dexamethasone prolongs the duration of single-
injection peripheral nerve block when added to the local anesthetic solution. Postulated …

In recent anesthetic practice, peripheral nerve blocks (PNBs) are used extensively for
surgical anesthesia and nonsurgical analgesia. PNBs offer many benefits over other …