Recent trends in chiral supercritical fluid chromatography

C West - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
This paper presents a review of the recent literature covering separations of enantiomers
achieved with supercritical fluid chromatography (SFC) or subcritical fluid chromatography …

Recent developments in preparative-scale supercritical fluid-and liquid chromatography for chiral separations

D Speybrouck, M Howsam, E Lipka - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
This review covers preparative-scale chromatography for enantioseparations in both
supercritical fluid and liquid chromatography published between 2016 and 2020. When …

Analytical Strategy for Low-Level Estimation of Unstable Genotoxic Boronate Ester Impurities

BS Kushwah, S Gandhi, D Purandharan… - … Process Research & …, 2024 - ACS Publications
Boronate esters are commonly used starting materials in the Suzuki–Miyaura coupling
reaction for the C–C bond formation due to their cost-effectiveness and ease of …

Large‐scale chiral supercritical fluid chromatography of a key intermediate in the synthesis of two S1P1 final active pharmaceutical ingredients

SH Yip, DR Wu, J Kempson, A Hernandez… - Separation …, 2019 - Wiley Online Library
Large‐scale preparation of two sphingosine‐1‐phosphate‐subtype 1 (S1P1) active
pharmaceutical ingredients, BMS‐986166 and compound 2, was achieved through a …