Sticky signaling—adhesion class G protein–coupled receptors take the stage
T Langenhan, G Aust, J Hamann - Science signaling, 2013 - science.org
Adhesion-type heterotrimeric guanine nucleotide–binding protein (G protein)–coupled
receptors (Adhesion-GPCRs) comprise a class of widely distributed seven-transmembrane …
receptors (Adhesion-GPCRs) comprise a class of widely distributed seven-transmembrane …
Adhesion G protein–coupled receptors—Candidate metabotropic mechanosensors and novel drug targets
T Langenhan - Basic & clinical pharmacology & toxicology, 2020 - Wiley Online Library
While a wide range of G protein‐coupled receptors (GPCR) have emerged as prime targets
for pharmacological intervention long ago, a distinct group of GPCR has only recently been …
for pharmacological intervention long ago, a distinct group of GPCR has only recently been …
TRIP8b splice variants form a family of auxiliary subunits that regulate gating and trafficking of HCN channels in the brain
B Santoro, RA Piskorowski, P Pian, L Hu, H Liu… - Neuron, 2009 - cell.com
Hyperpolarization-activated cyclic nucleotide-regulated (HCN) channels, which generate the
I h current, mediate a number of important brain functions. The HCN1 isoform regulates …
I h current, mediate a number of important brain functions. The HCN1 isoform regulates …
Clathrin-mediated endocytosis and adaptor proteins
NV Popova, IE Deyev, AG Petrenko - Acta Naturae (англоязычная …, 2013 - cyberleninka.ru
Macromolecules gain access to the cytoplasm of eukaryotic cells using one of several ways
of which clathrin-dependent endocytosis is the most researched. Although the mechanism of …
of which clathrin-dependent endocytosis is the most researched. Although the mechanism of …
TRIP8b regulates HCN1 channel trafficking and gating through two distinct C-terminal interaction sites
B Santoro, L Hu, H Liu, A Saponaro, P Pian… - Journal of …, 2011 - Soc Neuroscience
Hyperpolarization-activated cyclic nucleotide-regulated (HCN) channels in the brain
associate with their auxiliary subunit TRIP8b (also known as PEX5R), a cytoplasmic protein …
associate with their auxiliary subunit TRIP8b (also known as PEX5R), a cytoplasmic protein …
The structure and function of TRIP8b, an auxiliary subunit of hyperpolarization-activated cyclic-nucleotide gated channels
Y Han, KA Lyman, KM Foote, DM Chetkovich - Channels, 2020 - Taylor & Francis
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are expressed
throughout the mammalian central nervous system (CNS). These channels have been …
throughout the mammalian central nervous system (CNS). These channels have been …
The latrophilins,“split-personality” receptors
JP Silva, YA Ushkaryov - Adhesion-GPCRs: Structure to Function, 2010 - Springer
Latrophilin, a neuronal “adhesion-G protein-coupled receptor”, is the major brain receptor for
α-latrotoxin, a black widow spider toxin which stimulates strong neuronal exocytosis in …
α-latrotoxin, a black widow spider toxin which stimulates strong neuronal exocytosis in …
Latrophilins updated
DG Meza-Aguilar, AA Boucard - Biomolecular concepts, 2014 - degruyter.com
Latrophilins (LPHN) are part of a yet unexplored family of receptors comprising three
isoforms, LPHN1-3, and belonging to a unique branch of G protein-coupled receptors …
isoforms, LPHN1-3, and belonging to a unique branch of G protein-coupled receptors …
Activation of GABAB Receptors Ameliorates Cognitive Impairment via Restoring the Balance of HCN1/HCN2 Surface Expression in the Hippocampal CA1 Area in …
C Li, Y Lu, M Zhou, X Zong, C Li, X Xu, L Guo… - Molecular …, 2014 - Springer
Hyperpolarization-activated cyclic-nucleotide-gated cation nonselective (HCN) channels are
involved in the pathology of nervous system diseases. HCN channels and γ-aminobutyric …
involved in the pathology of nervous system diseases. HCN channels and γ-aminobutyric …
Imbalance of HCN1 and HCN2 expression in hippocampal CA1 area impairs spatial learning and memory in rats with chronic morphine exposure
M Zhou, P Luo, Y Lu, C Li, D Wang, Q Lu, X Xu… - Progress in Neuro …, 2015 - Elsevier
The hyperpolarization-activated cyclic-nucleotide-gated non-selective cation (HCN)
channels play a vital role in the neurological basis underlying nervous system diseases …
channels play a vital role in the neurological basis underlying nervous system diseases …