The antibacterial activity of fluoroquinolone derivatives: An update (2018–2021)

Y Jia, L Zhao - European journal of medicinal chemistry, 2021 - Elsevier
Bacterial infection is amongst the most common diseases in community and hospital
settings. Fluoroquinolones, exerting the antibacterial activity through binding to type II …

Recent advances in the synthesis and biological activity of 8-hydroxyquinolines

HA Saadeh, KA Sweidan, MS Mubarak - Molecules, 2020 - mdpi.com
Compounds containing the 8-hydroxyquinoline (8-HQ) 1 nucleus exhibit a wide range of
biological activities, including antimicrobial, anticancer, and antifungal effects. The chemistry …

Novel antimicrobial 8-hydroxyquinoline-based agents: Current development, structure–activity relationships, and perspectives

AR Joaquim, MP Gionbelli, G Gosmann… - Journal of Medicinal …, 2021 - ACS Publications
The search for new antimicrobials is imperative due to the emergent resistance of new
microorganism strains. In this context, revisiting known classes like 8-hydroxyquinolines …

Fluoroquinolones' biological activities against laboratory microbes and cancer cell lines

GARY Suaifan, AAM Mohammed, BA Alkhawaja - Molecules, 2022 - mdpi.com
Development of novel derivatives to rein in and fight bacteria have never been more
demanding, as microbial resistance strains are alarmingly increasing. A multitude of new …

High-Throughput Discovery of Synthetic Siderophores for Trojan Horse Antibiotics

BS Weber, NE Ritchie, S Hilker, DCK Chan… - ACS Infectious …, 2024 - ACS Publications
To cause infection, bacterial pathogens must overcome host immune factors and barriers to
nutrient acquisition. Reproducing these aspects of host physiology in vitro has shown great …

The antibacterial potential of ciprofloxacin hybrids against Staphylococcus aureus

W Zang, D Li, L Gao, S Gao, P Hao… - Current Topics in …, 2022 - ingentaconnect.com
Staphylococcus aureus (S. aureus), an important pathogen of both humans and animals,
can cause a variety of infections at any site of the body. The evolution of S. aureus …

[HTML][HTML] Synthesis and biological applications of some novel 8-Hydroxyquinoline urea and thiourea derivatives

MA Khasawneh, A AlKaabi, A Samadi, P Antony… - Arabian Journal of …, 2022 - Elsevier
A number of novel urea and thiourea derivatives of 8-hydroxyquinoline have been designed,
synthesized and evaluated for their anticancer activities. The structures of the new …

Electronic spectroscopic characterization of the formation of iron (III) metal complexes: the 8-HydroxyQuinoline as ligand case study

TH Vu, N Serradji, M Seydou, É Brémond… - Journal of Inorganic …, 2020 - Elsevier
Synthetic siderophores derivated from 8-HydroxyQuinoline (HQ) present various biological
and pharmacological activities, such as anti-neurodegenerative or anti-oxydative. However …

Rapid Synthesis of Covalent Organic Framework at Room Temperature Incorporated Electrospun Nanofiber for Thin Film Microextraction of Quinolone Antibiotics in …

A Chen, X Su, Y Zhou, WB Cheng, X He… - Journal of …, 2024 - Wiley Online Library
In this work, the covalent organic frameworks–incorporated electrospun nanofiber
membranes were used as a highly efficient adsorbent to enrich quinolone antibiotics in food …

Stochastic modeling of in vitro bactericidal potency

A Bogdanov, P Kevei, M Szalai, D Virok - Bulletin of Mathematical Biology, 2022 - Springer
Abstract We provide a Galton–Watson model for the growth of a bacterial population in the
presence of antibiotics. We assume that bacterial cells either die or duplicate, and the …