A Vezzani, S Balosso, T Ravizza - Nature Reviews Neurology, 2019 - nature.com
Epilepsy is a chronic neurological disease characterized by an enduring propensity for generation of seizures. The pathogenic processes of seizure generation and recurrence are …
Increasing evidence corroborates the fundamental role of neuroinflammation in the development of epilepsy. Proinflammatory cytokines (PICs) are crucial contributors to the …
R Wickstrom, O Taraschenko, R Dilena, ET Payne… - …, 2022 - Wiley Online Library
Objective This study was undertaken to develop consensus‐based recommendations for the management of adult and pediatric patients with new onset refractory status epilepticus …
The blood–brain barrier (BBB) is a highly specialized neurovascular unit, initially described as an intact barrier to prevent toxins, pathogens, and potentially harmful substances from …
QP Verhoog, L Holtman, E Aronica… - Frontiers in …, 2020 - frontiersin.org
Astrocytes are key homeostatic regulators in the central nervous system and play important roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …
S Koh, N Dupuis, S Auvin - Epilepsy Research, 2020 - Elsevier
The high-fat, low-carbohydrate ketogenic diet (KD) is an established treatment for drug- resistant epilepsy with a proven efficacy. The KD is being explored for Febrile Infection …
G Terrone, S Balosso, A Pauletti, T Ravizza… - …, 2020 - Elsevier
Neuroinflammation and reactive oxygen and nitrogen species are rapidly induced in the brain after acute cerebral injuries that are associated with an enhanced risk for epilepsy in …
One of the most important characteristics of the brain compared to other organs is its elevated metabolic demand. Consequently, neurons consume high quantities of oxygen …
YC Lai, E Muscal, E Wells, N Shukla… - Annals of clinical …, 2020 - Wiley Online Library
Febrile‐infection related epilepsy syndrome (FIRES) is a devastating neurological condition characterized by a febrile illness preceding new onset refractory status epilepticus (NORSE) …