Epithelial cells are the most common cell type in all animals, forming the sheets and tubes
that compose most organs and tissues. Apical–basal polarity is essential for epithelial cell …

The epithelial-mesenchymal transition (EMT) represents a biological program during which
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …

Abstract Human-pluripotent-stem-cell-derived kidney cells (hPSC-KCs) have important
potential for disease modelling and regeneration. Whether the hPSC-KCs can reconstitute …

The lung must maintain a proper barrier between airspaces and fluid filled tissues in order to
maintain lung fluid balance. Central to maintaining lung fluid balance are epithelial cells …

The most important obstacle to the drug delivery into the brain is the presence of the blood–
brain barrier, which limits the traffic of substances between the blood and the nervous tissue …

Epithelial cells undergo dynamic polarity changes as organs pattern, but the relationship
between epithelial polarity and cell fate is poorly understood. Using the developing lung as …

Epithelial permeability is a hallmark of mucosal inflammation, but the molecular mechanisms
involved remain poorly understood. A key component of the epithelial barrier is the apical …

Formation of tissue barriers by epithelial and endothelial cells requires neighbouring cells to
interact via intercellular junctions, which includes tight junctions. Tight junctions form a …

The morphology and structure of the intestinal epithelium are rearranged dynamically during
development, tissue regeneration, and disease progression. The most important …

The vertebrate small intestine requires an enormous surface area to effectively absorb
nutrients from food. Morphological adaptations required to establish this extensive surface …