Cancer is one of the dreadful diseases worldwide. Surgery, radiation and chemotherapy, are
the three basic standard modes of cancer treatment. However, difficulties in cancer treatment …

Beside inherited muscle diseases many catabolic conditions such as insulin resistance,
malnutrition, cancer growth, aging, infections, chronic inflammatory status, inactivity, obesity …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Background & Aims Pancreatic cancer has the highest prevalence of cancer-associated
cachexia among all cancers. ZIP4 promotes pancreatic cancer progression by regulating …

Cancer cachexia (CC) is a multifactorial syndrome characterized by systemic inflammation,
uncontrolled weight loss and dramatic metabolic alterations. This includes myofibrillar …

Significance: Cancer is frequently associated with the early appearance of cachexia, a
multifactorial wasting syndrome. If not present at diagnosis, cachexia develops either as a …

Modulation of immune responses by nutrients is an important area of study in cellular
biology and clinical sciences in the context of cancer therapies and anti-pathogen-directed …

Cancer cachexia is a lethal metabolic syndrome featuring muscle wasting with preferential
loss of fast-twitching muscle mass through an undefined mechanism. Here, we show that …

Cell fate determination is a complex process that is frequently described as cells traveling on
rugged pathways, beginning with DNA damage response (DDR). Tumor protein p53 (p53) …

Simple Summary An uncontrollable loss in the skeletal muscle of cancer patients which
leads to a significant reduction in body weight is clinically referred to as cancer cachexia …