[HTML][HTML] Comparative evaluation of rivastigmine permeation from a transdermal system in the Franz cell using synthetic membranes and pig ear skin with in vivo-in …

A Simon, MI Amaro, AM Healy, LM Cabral… - International journal of …, 2016 - Elsevier
In the present study, in vitro permeation experiments in a Franz diffusion cell were performed
using different synthetic polymeric membranes and pig ear skin to evaluate a rivastigmine …

[PDF][PDF] Development and evaluation of gastroretentive controlled release polymeric suspensions containing ciprofloxacin and carbopol polymers

S Sahoo, CK Chakraborti, PK Behera - J Chem Pharm Res, 2012 - researchgate.net
Considering the importance of drug release pattern from polymers, controlled release oral
formulations of Ciprofloxacin were prepared using two grades of Carbopol polymer such as …

Pharmacokinetic properties and tolerability of low-dose SoluMatrix diclofenac

PJ Desjardins, K Olugemo, D Solorio, CL Young - Clinical Therapeutics, 2015 - Elsevier
Purpose This study compared the pharmacokinetic properties and safety profile of low-dose
(18-and 35-mg) diclofenac capsules manufactured using SoluMatrix Fine Particle …

[HTML][HTML] Pharmacokinetics and pharmacodynamics of gliclazide from immediate and modified release formulation tablets in rats

M Resztak, TW Hermann, W Sawicki… - Iranian Journal of …, 2014 - ncbi.nlm.nih.gov
The objective of the study was to compare pharmacokinetic and pharmacodynamic
parameters of gliclazide after administration of immediate (IR) and modified release (MR) …

Pharmacokinetics and safety of low-dose submicron indomethacin 20 and 40 mg compared with indomethacin 50 mg

K Olugemo, D Solorio, C Sheridan… - Postgraduate …, 2015 - Taylor & Francis
Introduction. Indomethacin is a potent analgesic that, similar to other nonsteroidal anti-
inflammatory drugs, is associated with serious dose-related adverse events. There is a need …

A novel bile salts–lipase polymeric film-infused minitablet system for enhanced oral delivery of cholecalciferol

MC Braithwaite, YE Choonara, P Kumar… - Pharmaceutical …, 2016 - Taylor & Francis
Few researchers have investigated the use of multiple physiological enhancers combined
with synthetic carriers to augment delivery of nutraceuticals. The current work describes the …

Preliminary evaluation of the in vitro release and in vivo absorption in rabbits of the modified-release dosage forms

AA Petrovic, SM Petricevic, SM Ristic… - Drug Development …, 2013 - Taylor & Francis
Objective: The suitability of the rabbit as an animal model for the primary screening and
selection of the pilot scale batches during the early stages of the formulation development …

Regulatory pathway to introduce a nanomedicine product in the market at international level

S Singh, N Molugulu, L Devi, V Singh… - Theory and Applications …, 2021 - Elsevier
Nanotechnology-enabled medical technologies will have a huge impact on human disease
detection, prevention, and treatment over the next couple of decades. Nanomedicines have …

[图书][B] Physicochemical Characterization and Biological Evaluation of Solid Dispersions of Anticancer Agent Betulinic Acid

M Yu - 2015 - search.proquest.com
Poor water soluble drugs face major hurdles in the drug development process due to
inadequate bioavailability. Betulinic acid (BA) is one such poorly soluble compound (0.02 …

An in vitro-in vivo correlation study of modified release formulations of Venlafaxine. HCl

JR Aravindaraj, D Manikandan… - Revista de Ciências …, 2014 - rcfba.fcfar.unesp.br
A single dose, randomized, complete and four treatment cross over study was conducted in
healthy human subjects for IVIVC of venlafaxine. HCl. Plasma concentrations were …