Immune modulation by curcumin: The role of interleukin-10
Cytokines are small secreted proteins released by different types of cells with specific effects
on cellular signaling and communication via binding to their receptors on the cell surface. IL …
on cellular signaling and communication via binding to their receptors on the cell surface. IL …
Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease
SS Iyer, G Cheng - Critical Reviews™ in Immunology, 2012 - dl.begellhouse.com
ABSTRACT Interleukin 10 (IL-10) is a cytokine with potent anti-inflammatory properties that
plays a central role in limiting host immune response to pathogens, thereby preventing …
plays a central role in limiting host immune response to pathogens, thereby preventing …
The regulation of IL-10 production by immune cells
M Saraiva, A O'garra - Nature reviews immunology, 2010 - nature.com
Abstract Interleukin-10 (IL-10), a cytokine with anti-inflammatory properties, has a central
role in infection by limiting the immune response to pathogens and thereby preventing …
role in infection by limiting the immune response to pathogens and thereby preventing …
Regulation and functions of the IL-10 family of cytokines in inflammation and disease
The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …
The role of the transcription factor CREB in immune function
AY Wen, KM Sakamoto, LS Miller - The Journal of Immunology, 2010 - journals.aai.org
CREB is a transcription factor that regulates diverse cellular responses, including
proliferation, survival, and differentiation. CREB is induced by a variety of growth factors and …
proliferation, survival, and differentiation. CREB is induced by a variety of growth factors and …
Interleukin‐10: new perspectives on an old cytokine
DM Mosser, X Zhang - Immunological reviews, 2008 - Wiley Online Library
Interleukin‐10 (IL‐10) has long been recognized to have potent and broad‐spectrum anti‐
inflammatory activity, which has been unequivocally established in various models of …
inflammatory activity, which has been unequivocally established in various models of …
Keynote review: phosphodiesterase-4 as a therapeutic target
MD Houslay, P Schafer, KYJ Zhang - Drug discovery today, 2005 - Elsevier
Cyclic AMP (cAMP) is a key second messenger in all cells. It is compartmentalized within
cells and its levels are controlled, as a result of spatially discrete signaling cassettes …
cells and its levels are controlled, as a result of spatially discrete signaling cassettes …
Microbial manipulation of receptor crosstalk in innate immunity
G Hajishengallis, JD Lambris - Nature Reviews Immunology, 2011 - nature.com
In the arms race of host–microbe co-evolution, successful microbial pathogens have evolved
ingenious ways to evade host immune responses. In this Review, we focus on'crosstalk …
ingenious ways to evade host immune responses. In this Review, we focus on'crosstalk …
Molecular mechanisms for cAMP-mediated immunoregulation in T cells–role of anchored protein kinase a signaling units
VL Wehbi, K Taskén - Frontiers in immunology, 2016 - frontiersin.org
The cyclic AMP/protein kinase A (cAMP/PKA) pathway is one of the most common and
versatile signal pathways in eukaryotic cells. A-kinase anchoring proteins (AKAPs) target …
versatile signal pathways in eukaryotic cells. A-kinase anchoring proteins (AKAPs) target …
An anti-infective peptide that selectively modulates the innate immune response
MG Scott, E Dullaghan, N Mookherjee, N Glavas… - Nature …, 2007 - nature.com
We show that an innate defense–regulator peptide (IDR-1) was protective in mouse models
of infection with important Gram-positive and Gram-negative pathogens, including methicillin …
of infection with important Gram-positive and Gram-negative pathogens, including methicillin …