Potential of Central, Eastern and Western Africa medicinal plants for cancer therapy: spotlight on resistant cells and molecular targets

AT Mbaveng, V Kuete, T Efferth - Frontiers in Pharmacology, 2017 - frontiersin.org
Cancer remains a major health hurdle worldwide and has moved from the third leading
cause of death in the year 1990 to second place after cardiovascular disease since 2013 …

Phytochemicals in prostate cancer: from bioactive molecules to upcoming therapeutic agents

B Salehi, PVT Fokou, LRT Yamthe, BT Tali… - Nutrients, 2019 - mdpi.com
Prostate cancer is a heterogeneous disease, the second deadliest malignancy in men and
the most commonly diagnosed cancer among men. Traditional plants have been applied to …

In vitro cytotoxic activity of medicinal plants from Nigeria ethnomedicine on Rhabdomyosarcoma cancer cell line and HPLC analysis of active extracts

OO Ogbole, PA Segun, AJ Adeniji - BMC complementary and alternative …, 2017 - Springer
Background Cancer is a leading cause of death world-wide, with approximately 17.5 million
new cases and 8.7 million cancer related deaths in 2015. The problems of poor selectivity …

In vitro antiviral activity of twenty-seven medicinal plant extracts from Southwest Nigeria against three serotypes of echoviruses

OO Ogbole, TE Akinleye, PA Segun, TC Faleye… - Virology journal, 2018 - Springer
Background Echoviruses, a serotype of enteroviruses, infect millions of people globally and
there is no specific drug treatment or vaccine available for its management. The screening of …

[HTML][HTML] Ferulic acid exerts anti-angiogenic and anti-tumor activity by targeting fibroblast growth factor receptor 1-mediated angiogenesis

GW Yang, JS Jiang, WQ Lu - International Journal of Molecular Sciences, 2015 - mdpi.com
Most anti-angiogenic therapies currently being evaluated target the vascular endothelial
growth factor (VEGF) pathway; however, the tumor vasculature can acquire resistance to …

Daidzein: A review of pharmacological effects

MY Sun, Y Ye, L Xiao, K Rahman, W Xia… - African journal of …, 2016 - ajol.info
Background: Daidzein is an isoflavone with extensive nutritious value and is mainly
extracted from soy plants. It is also called phytoestrogen due to its structural similarity to the …

Medicinal plants used in the management of cancer among the Ijebus of Southwestern Nigeria

PA Segun, OO Ogbole, EO Ajaiyeoba - Journal of herbal medicine, 2018 - Elsevier
Abstract Ethnopharmacological relevance The Ijebu ethnic group of southwestern Nigeria
has a rich tradition of medicinal plant use. Interestingly, individuals from developing …

Mangiferin inhibits apoptosis in doxorubicin-induced vascular endothelial cells via the Nrf2 signaling pathway

MB Ismail, P Rajendran, HM AbuZahra… - International Journal of …, 2021 - mdpi.com
Doxorubicin increases endothelial permeability, hence increasing cardiomyocytes' exposure
to doxorubicin (DOX) and exposing myocytes to more immediate damage. Reactive oxygen …

[PDF][PDF] Chicken embryo: a useful animal model for drug testing?

LNM Ribeiro, AE Schlemper… - European Review for …, 2022 - europeanreview.org
The use of chicken embryos (CEs) as an in vivo experimental model for different
pharmaceutical purposes is not a novelty. However, in recent years, the number of reports …

Unlocking daidzein's healing power: Present applications and future possibilities in phytomedicine

P Goleij, PM Sanaye, W Alam, J Zhang, MAK Tabari… - Phytomedicine, 2024 - Elsevier
Background Cancer is one of the leading causes of death and a great threat to people
around the world. Cancer treatment modalities include surgery, radiotherapy, chemotherapy …