Brain atrophy measured by MRI is a potentially useful tool for monitoring disease
progression in multiple sclerosis. The location, extent and mechanisms of brain atrophy in …

Relative to the gray matter, there is a paucity of information regarding white matter
biochemical alterations and their contribution to Alzheimer's disease (AD). Biochemical …

Brain-predicted age difference scores are calculated by subtracting chronological age from
'brain'age, which is estimated using neuroimaging data. Positive scores reflect accelerated …

This article reviews recent studies of magnetic resonance imaging and magnetic resonance
spectroscopy in demen tia, including Alzheimer's disease, frontotemporal dementia …

Purpose To investigate the reproducibility of SPM99‐based whole brain, gray matter, and
white matter volume measurements with and without image inhomogeneity correction …

Studies of presenilin (PSEN) gene mutations producing early onset Alzheimer's disease
(AD) have helped elucidate the pathogenic mechanisms of dementia and guided clinical …

APP23 transgenic mice overexpressing amyloid precursor protein (APP751) reproduce
neuropathological changes associated with Alzheimer's disease such as high levels of …

Background and Purpose—Brain atrophy, cortical infarction, and subcortical ischemic
vasculopathy have all been associated with cognitive dysfunction. The interrelationships …

We present global and regional rates of brain atrophy measured on serially acquired T1-
weighted brain MR images for a group of Alzheimer's disease (AD) patients and age …

The white matter (WM) represents approximately half the cerebrum volume and is
profoundly affected in Alzheimer's disease (AD). However, both the WM responses to AD as …