Ferredoxin 1 is essential for embryonic development and lipid homeostasis

S Mohibi, Y Zhang, V Perng, M Chen, J Zhang, X Chen - Elife, 2024 - elifesciences.org
Abstract Mammalian ferredoxin 1 and 2 (FDX1/2) belong to an evolutionary conserved
family of iron-sulfur cluster containing proteins and act as electron shutters between …

[HTML][HTML] Ninjurin 2 modulates tumorigenesis, inflammation, and metabolism via pyroptosis

J Zhang, X Kong, HJ Yang, W Zhang, M Chen… - The American Journal of …, 2024 - Elsevier
The nerve injury induced protein 2 (NINJ2) belongs to a family of homophilic adhesion
molecules and was initially found to be involved in nerve regeneration. However, the role of …

[HTML][HTML] Ferredoxin 2 is critical for tumor suppression and lipid homeostasis but dispensable for embryonic development

J Zhang, Y Zhang, S Mohibi, V Perng… - The American Journal of …, 2024 - Elsevier
Abstract Ferredoxin 1 and 2 (FDX1/2) constitute an evolutionarily conserved FDX family of
iron-sulfur cluster (ISC) containing proteins. FDX1/2 are cognate substrates of ferredoxin …

Genetically predicted TWEAK mediates the association between lipidome and Keratinocyte Carcinomas

H Lei, X Chen, R Bai, Q Wang, N Xian… - Skin Research and …, 2024 - Wiley Online Library
Background Reports suggest that lipid profiles may be linked to the likelihood of developing
skin cancer, yet the exact causal relationship is still unknown. Objective This study aimed to …

[HTML][HTML] An integrated analysis of dysregulated SCD1 in human cancers and functional verification of miR-181a-5p/SCD1 axis in esophageal squamous cell …

BY Wang, YY Chang, LY Shiu, YJ Lee, YW Lin… - Computational and …, 2023 - Elsevier
Esophageal squamous cell carcinoma (ESCC), one of the most lethal cancers, has become
a global health issue. Stearoyl-coA desaturase 1 (SCD1) has been demonstrated to play a …

Anti-cancer bioactive peptide induces apoptosis in gastric cancer cells through TP53 signaling cascade

Q Suyila, X Li, X Su - 2024 - researchsquare.com
Our previous studies show that anti-cancer bioactive peptide (ACBP) inhibits the initiation
and progression of gastric cancer via apoptosis and cell cycle arrest, however, the …

[PDF][PDF] Význam alternativního sestřihu v rodině p53

K KUBOVÁ - is.muni.cz
Rodina nádorového supresoru p53 zahrnuje tři zástupce: p53, p63 a p73. Ty se v rámci
transkriptomu a proteomu člověka mohou vyskytovat v několika izoformách lišících se svou …