This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Carbohydrates are the most abundant organic compounds in nature, widely distributed in
animals, plants and microorganisms. In order to understanding their structure properties, the …

Despite the recent advances in mass spectrometry (MS)-based methods for glycan structural
analysis, characterization of glycomes remains a significant analytical challenge, in part due …

N-linked glycosylation is one of the most important post-translational modifications of
proteins. Current knowledge of multicellular eukaryote N-glycan biosynthesis suggests high …

N-linked glycosylation is one of the most important protein post-translational modifications.
Despite the importance of N-glycans, the structural determination of N-glycan isomers …

Mass spectrometry (MS) has become the central technique that is extensively used for the
analysis of molecular structures of unknown compounds in the gas phase. It manipulates the …

Free oligosaccharides are abundant macronutrients in milk and involved in prebiotic
functions and antiadhesive binding of viruses and pathogenic bacteria to colonocytes …

Despite the essential role that glycans play in many biological processes, their isomeric
complexity makes their structural determination particularly challenging. Tandem mass …

We herein reported the first chemoenzymatic synthesis of lacto-N-hexaose (LNH) by
combining chemical carbohydrate synthesis with a selectively enzymatic glycosylation …

Despite the importance of carbohydrates in biological systems, structural determination of
carbohydrates remains difficult because of the large number of isomers. In this study, a new …