Single-cell analysis has become an established method to study cell heterogeneity and for
rare cell characterization. Despite the high cost and technical constraints, applications are …

Frozen biospecimens are crucial for translational research and contain well‐preserved
nucleic acids and protein. However, the risks of freezer failure as well as space, cost, and …

Formalin is a widely used fixative but there is potential public health risks to exposure.
Besides, alcoholic fixation is advantageous over formalin fixation because of faster fixation …

Although the extraction and analysis of nucleic acids from formalin-fixed paraffin-embedded
tissues is a routine and growing part of pathology practice, no generally accepted …

Fixation with formalin, a widely adopted procedure to preserve tissue samples, leads to
extensive degradation of nucleic acids and thereby compromises procedures like microarray …

Analysis of RNA isolated from fixed and paraffin-embedded tissues is widely used in
biomedical research and molecular pathological diagnostics. We have performed a …

The lack of standardization of tissue handling and processing hinders the development and
validation of new biomarkers in research and clinical settings. We compared the …

Because formaldehyde is toxic and creates cross-links that may hinder
immunohistochemical studies, we tested 3 new cross-linking (F-Solv [Adamas, Rhenen, the …

Formalin-fixed paraffin-embedded (FFPE) tissue is the predominant preparation for
diagnostic histopathological evaluation and increasingly the biospecimen on which …

Background: In prostate adenocarcinoma, the dissection of the expression behaviour of the
eukaryotic elongation factors (eEF1A1/2) has not yet fully elucidated. Methods: The …