[HTML][HTML] Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity—Diverse effects on cell growth, metabolism and cancer
JA McCubrey, D Rakus, A Gizak, LS Steelman… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Abstract Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase that participates
in an array of critical cellular processes. GSK-3 was first characterized as an enzyme that …
in an array of critical cellular processes. GSK-3 was first characterized as an enzyme that …
Hedgehog signaling pathway as genetic and epigenetic target in ovarian tumors
Background: Hedgehog signaling pathway is a developmental pathway mostly inactive in
adult tissues, with the exception of stem cells. It is often found upregulated in various tumors …
adult tissues, with the exception of stem cells. It is often found upregulated in various tumors …
[HTML][HTML] Non-canonical Hedgehog signaling activation in ovarian borderline tumors and ovarian carcinomas
Hedgehog signaling pathway has been implicated in the pathology of ovarian cancer, and
Survivin (BIRC5) has been suggested as a novel target of this pathway. Herein we …
Survivin (BIRC5) has been suggested as a novel target of this pathway. Herein we …
Combination of cyclopamine and tamoxifen promotes survival and migration of mcf-7 breast cancer cells–interaction of Hedgehog-Gli and estrogen receptor signaling …
Hedgehog-Gli (Hh-Gli) signaling pathway is one of the new molecular targets found
upregulated in breast tumors. Estrogen receptor alpha (ERα) signaling has a key role in the …
upregulated in breast tumors. Estrogen receptor alpha (ERα) signaling has a key role in the …
Retracted: The Effect of PTCH1 on Ovarian Cancer Cell Proliferation and Apoptosis
F Zheng, X Xiao, C Wang - Cancer biotherapy & …, 2019 - liebertpub.com
Cancer Biotherapy and Radiopharmaceuticals officially retracts the paper entitled,“The
Effect of PTCH1 on Ovarian Cancer Cell Proliferation and Apoptosis,” by Fang Zheng, Xinyi …
Effect of PTCH1 on Ovarian Cancer Cell Proliferation and Apoptosis,” by Fang Zheng, Xinyi …
Gynecological Pathology
A Malpica, ED Euscher, P Ramalingam… - Oncological Surgical …, 2020 - Springer
This chapter presents a specific anatomical site-centered review of neoplastic processes of
different lineages. Each section presents updated information covering clinical features …
different lineages. Each section presents updated information covering clinical features …
Low‐Grade Serous Carcinoma of the Ovary
AN Fader, A Malpica - Textbook of Uncommon Cancer, 2017 - Wiley Online Library
Low‐grade serous carcinoma is a rare tumor accounting for approximately 5% of ovarian
carcinomas. It usually originates in a stepwise fashion from a serous borderline tumor. Its …
carcinomas. It usually originates in a stepwise fashion from a serous borderline tumor. Its …
Re:“A Low-Grade Ovarian Carcinoma Case With Coincident LOH of PTCH1 and BRCA1, and a Mutation in BRCA1,” Int J Gyn Pathol 2012 May; 31: 264-271.
M Köbel, P Ghatage - International Journal of Gynecological …, 2013 - journals.lww.com
We read with interest the paper by Maurac et al.(1) reporting a case of low-grade serous
ovarian carcinoma with BRCA1 mutation. We are puzzled by the claim that ''this report …
ovarian carcinoma with BRCA1 mutation. We are puzzled by the claim that ''this report …