Neutrophil metalloproteinase driven spleen damage hampers infection control of trypanosomiasis
HTT Pham, S Magez, B Choi, B Baatar, J Jung… - Nature …, 2023 - nature.com
Recent blood transcriptomic analysis of rhodesiense sleeping sickness patients has
revealed that neutrophil signature genes and activation markers constitute the top indicators …
revealed that neutrophil signature genes and activation markers constitute the top indicators …
Antifibrotic Drugs against Idiopathic Pulmonary Fibrosis and Pulmonary Fibrosis Induced by COVID-19: Therapeutic Approaches and Potential Diagnostic Biomarkers
A Perez-Favila, I Garza-Veloz… - International Journal of …, 2024 - mdpi.com
The COVID-19 pandemic has had a significant impact on the health and economy of the
global population. Even after recovery from the disease, post-COVID-19 symptoms, such as …
global population. Even after recovery from the disease, post-COVID-19 symptoms, such as …
Gene expression profile analysis of severe influenza-based modulation of idiopathic pulmonary fibrosis
J Kong, L Chen - European Journal of Medical Research, 2024 - Springer
Background It is known severe influenza infections and idiopathic pulmonary fibrosis (IPF)
disease might stimulate each other. Till now, no associated mechanism has been reported …
disease might stimulate each other. Till now, no associated mechanism has been reported …
Unraveling the pathogenic interplay between SARS-CoV-2 and polycystic ovary syndrome using bioinformatics and experimental validation
H Bai, S Zhang, J Huang, K Diao, C Li, M Wang - Scientific Reports, 2024 - nature.com
The prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among
polycystic ovary syndrome (PCOS) is significantly higher than in the general population …
polycystic ovary syndrome (PCOS) is significantly higher than in the general population …
Identification of shared pathogenetic mechanisms between COVID-19 and IC through bioinformatics and system biology
Z Sun, L Zhang, R Wang, Z Wang, X Liang, J Gao - Scientific Reports, 2024 - nature.com
COVID-19 increased global mortality in 2019. Cystitis became a contributing factor in SARS-
CoV-2 and COVID-19 complications. The complex molecular links between cystitis and …
CoV-2 and COVID-19 complications. The complex molecular links between cystitis and …
Proteomic signatures of vaccine-induced and breakthrough infection-induced host responses to SARS-CoV-2
The severity of SARS-CoV-2 illness is influenced by factors including age, sex, pre-existing
health conditions, and individual immune responses. However, the mechanisms conferring …
health conditions, and individual immune responses. However, the mechanisms conferring …
Elevated ITGA1 levels in type 2 diabetes: implications for cardiac function impairment
M Su, Y Hou, S Cai, W Li, Y Wei, R Wang, M Wu, M Liu… - Diabetologia, 2024 - Springer
Aims/hypothesis Type 2 diabetes mellitus is known to contribute to the development of heart
failure with preserved ejection fraction (HFpEF). However, identifying HFpEF in individuals …
failure with preserved ejection fraction (HFpEF). However, identifying HFpEF in individuals …
NELL1 Variant Protein (NV1) modulates hyper-inflammation, Th-1 mediated immune response, and the HIF-1α hypoxia pathway to promote healing in viral-induced …
C Culiat, D Soni, W Malkes, M Wienhold… - Biochemical and …, 2024 - Elsevier
Research underscores the urgent need for technological innovations to treat lung tissue
damage from viral infections and the lasting impact of COVID-19. Our study demonstrates …
damage from viral infections and the lasting impact of COVID-19. Our study demonstrates …
Proteomic lung analysis revealed hyper-activation of neutrophil extracellular trap formation in cases of fatal COVID-19
S Song, L Zeng, J Xu, L Shi, L Lu, Y Ling, L Zhang - Heliyon, 2024 - cell.com
The molecular pathology of lung injury in patients with Corona Virus Disease 2019 (COVID-
19) remain unclear. In this study, we performed a proteomic study of lung tissues from seven …
19) remain unclear. In this study, we performed a proteomic study of lung tissues from seven …
Identification of key genes and biological pathways in chronic obstructive pulmonary disease using bioinformatics and next generation sequencing data analysis
BM Vastrad, CM Vastrad - bioRxiv, 2024 - biorxiv.org
Identification of accurate biomarkers is still particularly urgent for improving the poor survival
of chronic obstructive pulmonary disease (COPD) patients. In this investigation, we aimed to …
of chronic obstructive pulmonary disease (COPD) patients. In this investigation, we aimed to …