Mature myelinating oligodendrocytes, the cells that produce the myelin sheath that insulates
axons in the central nervous system, have distinct energetic and metabolic requirements …

Alzheimer's disease poses a significant global health challenge owing to the progressive
cognitive decline of patients and absence of curative treatments. The current therapeutic …

The molecules that constitute myelin are critical for the integrity of axon/myelin‐units and
thus speed and precision of impulse propagation. In the CNS, the protein composition of …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with cognitive
dysfunction, memory decline, and behavioral disturbance, and it is pathologically …

Background Cancer poses a major global health challenge, and immunotherapy, known as
the third revolution in cancer treatment, has brought new hope to patients. The emerging …

White matter (WM) abnormalities are an emerging feature of schizophrenia, yet the
underlying pathophysiological mechanisms are largely unknown. Disruption of ErbB …

Myelin sheaths comprise compacted layers of oligodendroglial membrane wrapped spirally
around axons. Each sheath, if imagined unwrapped, has a cytoplasm-filled space at its …

Myelin sheaths comprise compacted layers of oligodendroglial membrane wrapped spirally
around axons. Each sheath, if imagined unwrapped, has a cytoplasm-filled space at its …

Neurodegenerative pathologies including multiple sclerosis (MS) are consistently
associated with energy deficit in the central nervous system (CNS). This might directly …