Getting the Most Out of Enzyme Cascades: Strategies to Optimize In Vitro Multi-Enzymatic Reactions

R Siedentop, C Claaßen, D Rother, S Lütz… - Catalysts, 2021 - mdpi.com
In vitro enzyme cascades possess great benefits, such as their synthetic capabilities for
complex molecules, no need for intermediate isolation, and the shift of unfavorable equilibria …

Artificial Intelligence Methods and Models for Retro-Biosynthesis: A Scoping Review

G Gricourt, P Meyer, T Duigou, JL Faulon - ACS Synthetic Biology, 2024 - ACS Publications
Retrosynthesis aims to efficiently plan the synthesis of desirable chemicals by strategically
breaking down molecules into readily available building block compounds. Having a long …

RetroLens: A Human-AI Collaborative System for Multi-step Retrosynthetic Route Planning

C Shi, Y Hu, S Wang, S Ma, C Zheng, X Ma… - Proceedings of the 2023 …, 2023 - dl.acm.org
Multi-step retrosynthetic route planning (MRRP) is the core task in synthetic chemistry, in
which chemists recursively deconstruct a target molecule to find a set of reactants that make …

SynthLens: Visual Analytics for Facilitating Multi-step Synthetic Route Design

Q Wang, R Sheng, S Ruan, X Jin, C Shi… - arXiv preprint arXiv …, 2024 - arxiv.org
Designing synthetic routes for novel molecules is pivotal in various fields like medicine and
chemistry. In this process, researchers need to explore a set of synthetic reactions to …

Green biomanufacturing promoted by automatic retrobiosynthesis planning and computational enzyme design

Z Cui, S Zhang, S Zhang, B Chen, Y Zhu… - Chinese Journal of …, 2022 - Elsevier
Biomanufacturing, which uses renewable resources as raw materials and uses biological
processes to produce energy and chemicals, has long been regarded as a production …

Human-Ai Collaborative Approaches to Supporting Multi-Stage, Stochastic Multi-Criteria Decision Making

C Shi - 2023 - search.proquest.com
Multi-stage, stochastic multi-criteria decision making (MSMDM) is common in various
domains of human activity, such as scientific research and combinatorial games. These …

[PDF][PDF] Getting the Most Out of Enzyme Cascades: Strategies to Optimize In Vitro Multi-Enzymatic Reactions. Catalysts 2021, 11, 1183

R Siedentop, C Claaßen, D Rother, S Lütz… - 2021 - publications.rwth-aachen.de
In vitro enzyme cascades possess great benefits, such as their synthetic capabilities for
complex molecules, no need for intermediate isolation, and the shift of unfavorable equilibria …

[引用][C] Computer-Aided Synthesis Planning for Biocatalysis

W Finnigan - 2024 - Elsevier