Staphylococcus aureus is a major human pathogen causing a vast array of infections with
significant mortality. Its versatile physiology enables it to adapt to various environments …

A stable but reversible phenotype switch from normal to persister state is advantageous to
the intracellular pathogens to cause recurrent infections and to evade the host immune …

Recalcitrance of genetically susceptible bacteria to antibiotic killing is a hallmark of bacterial
drug tolerance. This phenomenon is prevalent in biofilms, persisters, and also planktonic …

Pathogenic bacterial persisters are responsible for the recalcitrance of chronic and
persistent infections to antimicrobial therapy. Although the mechanisms of persister …

Background: Bacterial persistence to antibiotics relates to the phenotypic ability to survive
lethal concentrations of otherwise bactericidal antibiotics. The quantitative nature of the time …

Persistence is a prime example of phenotypic heterogeneity, where a microbial population
splits into two distinct subpopulations with different growth and survival properties as a result …

Biofilm formation is a major pathogenicity strategy of Staphylococcus epidermidis causing
various medical-device infections. Persister cells have been implicated in treatment failure of …

Persisters form sub-populations of stress-tolerant cells that play a major role in the capacity
of biofilms to survive and recover from disturbances such as antibiotic treatments. The …

Persistent bacteremia caused by Staphylococcus aureus (SA), especially methicillin-
resistant SA (MRSA), is a significant cause of morbidity and mortality. Despite susceptibility …

Methicillin-resistant Staphylococcus aureus (MRSA) colonization increases the risk of
infection. Response to decolonization treatment is highly variable and determinants for …