[HTML][HTML] Mathematical Modeling and Inference of Epidermal Growth Factor-Induced Mitogen-Activated Protein Kinase Cell Signaling Pathways

J Feng, X Zhang, T Tian - International Journal of Molecular Sciences, 2024 - mdpi.com
The mitogen-activated protein kinase (MAPK) pathway is an important intracellular signaling
cascade that plays a key role in various cellular processes. Understanding the regulatory …

PCA-based synthetic sensitivity coefficients for chemical reaction network in cancer

G Biddau, G Caviglia, M Piana, S Sommariva - Scientific Reports, 2024 - nature.com
Chemical reaction networks are powerful tools for modeling cell signaling and its disruptions
in diseases like cancer. Realistic chemical reaction networks involve hundreds of proteins …

[引用][C] When algebra twinks system biology: a conjecture on the structure of Gr\" obner bases in complex chemical reaction networks

P Ferrari, S Sommariva, M Piana, F Benvenuto… - arXiv preprint arXiv …, 2025