Artificial intelligence in histopathology: enhancing cancer research and clinical oncology

A Shmatko, N Ghaffari Laleh, M Gerstung, JN Kather - Nature cancer, 2022 - nature.com
Artificial intelligence (AI) methods have multiplied our capabilities to extract quantitative
information from digital histopathology images. AI is expected to reduce workload for human …

Artificial intelligence for digital and computational pathology

AH Song, G Jaume, DFK Williamson, MY Lu… - Nature Reviews …, 2023 - nature.com
Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence,
including deep learning, have boosted the field of computational pathology. This field holds …

Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study

SJ Wagner, D Reisenbüchler, NP West, JM Niehues… - Cancer Cell, 2023 - cell.com
Deep learning (DL) can accelerate the prediction of prognostic biomarkers from routine
pathology slides in colorectal cancer (CRC). However, current approaches rely on …

Adversarial attacks and adversarial robustness in computational pathology

N Ghaffari Laleh, D Truhn, GP Veldhuizen… - Nature …, 2022 - nature.com
Artificial Intelligence (AI) can support diagnostic workflows in oncology by aiding diagnosis
and providing biomarkers directly from routine pathology slides. However, AI applications …

Generalizable biomarker prediction from cancer pathology slides with self-supervised deep learning: A retrospective multi-centric study

JM Niehues, P Quirke, NP West, HI Grabsch… - Cell reports …, 2023 - cell.com
Deep learning (DL) can predict microsatellite instability (MSI) from routine histopathology
slides of colorectal cancer (CRC). However, it is unclear whether DL can also predict other …

Self-supervised attention-based deep learning for pan-cancer mutation prediction from histopathology

OL Saldanha, CML Loeffler, JM Niehues… - NPJ Precision …, 2023 - nature.com
The histopathological phenotype of tumors reflects the underlying genetic makeup. Deep
learning can predict genetic alterations from pathology slides, but it is unclear how well …

Deep learning-based phenotyping reclassifies combined hepatocellular-cholangiocarcinoma

J Calderaro, N Ghaffari Laleh, Q Zeng, P Maille… - Nature …, 2023 - nature.com
Primary liver cancer arises either from hepatocytic or biliary lineage cells, giving rise to
hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICCA). Combined …

Neuropathologist-level integrated classification of adult-type diffuse gliomas using deep learning from whole-slide pathological images

W Wang, Y Zhao, L Teng, J Yan, Y Guo, Y Qiu… - Nature …, 2023 - nature.com
Current diagnosis of glioma types requires combining both histological features and
molecular characteristics, which is an expensive and time-consuming procedure …

Computational pathology in cancer diagnosis, prognosis, and prediction–present day and prospects

G Verghese, JK Lennerz, D Ruta, W Ng… - The Journal of …, 2023 - Wiley Online Library
Computational pathology refers to applying deep learning techniques and algorithms to
analyse and interpret histopathology images. Advances in artificial intelligence (AI) have led …

Vision transformers for computational histopathology

H Xu, Q Xu, F Cong, J Kang, C Han… - IEEE Reviews in …, 2023 - ieeexplore.ieee.org
Computational histopathology is focused on the automatic analysis of rich phenotypic
information contained in gigabyte whole slide images, aiming at providing cancer patients …