Synthetic biology tools to engineer microbial communities for biotechnology

NS McCarty, R Ledesma-Amaro - Trends in biotechnology, 2019 - cell.com
Microbial consortia have been used in biotechnology processes, including fermentation,
waste treatment, and agriculture, for millennia. Today, synthetic biologists are increasingly …

Quorum sensing for population-level control of bacteria and potential therapeutic applications

S Wu, J Liu, C Liu, A Yang, J Qiao - Cellular and Molecular Life Sciences, 2020 - Springer
Quorum sensing (QS), a microbial cell-to-cell communication process, dynamically regulates
a variety of metabolism and physiological activities. In this review, we provide an update on …

Quorum sensing in synthetic biology: A review

A Boo, RL Amaro, GB Stan - Current Opinion in Systems Biology, 2021 - Elsevier
In nature, quorum sensing is one of the mechanisms bacterial populations use to
communicate with their own species or across species to coordinate behaviours. For the last …

Quorum sensing communication: molecularly connecting cells, their neighbors, and even devices

S Wang, GF Payne, WE Bentley - Annual review of chemical …, 2020 - annualreviews.org
Quorum sensing (QS) is a molecular signaling modality that mediates molecular-based cell–
cell communication. Prevalent in nature, QS networks provide bacteria with a method to …

Single strain control of microbial consortia

AJH Fedorec, BD Karkaria, M Sulu… - Nature communications, 2021 - nature.com
The scope of bioengineering is expanding from the creation of single strains to the design of
microbial communities, allowing for division-of-labour, specialised sub-populations and …

Hard limits and performance tradeoffs in a class of antithetic integral feedback networks

N Olsman, AA Baetica, F Xiao, YP Leong, RM Murray… - Cell systems, 2019 - cell.com
Feedback regulation is pervasive in biology at both the organismal and cellular level. In this
article, we explore the properties of a particular biomolecular feedback mechanism called …

Construction of synthetic microbial ecosystems and the regulation of population proportion

W Jiang, X Yang, F Gu, X Li, S Wang, Y Luo… - ACS Synthetic …, 2022 - ACS Publications
With the development of synthetic biology, the design and application of microbial consortia
have received increasing attention. However, the construction of synthetic ecosystems is still …

Can we manage microbial systems to enhance carbon storage?

N Mahmoudi, RC Wilhelm - Environmental Microbiology, 2023 - Wiley Online Library
Climate change is an urgent environmental issue with wide‐ranging impacts on ecosystems
and society. Microbes are instrumental in maintaining the balance between carbon (C) …

Architectural principles for characterizing the performance of antithetic integral feedback networks

N Olsman, F Xiao, JC Doyle - Iscience, 2019 - cell.com
As we begin to design increasingly complex synthetic biomolecular systems, it is essential to
develop rational design methodologies that yield predictable circuit performance. Here we …

Toward engineering biosystems with emergent collective functions

TE Gorochowski, S Hauert, JU Kreft… - … in bioengineering and …, 2020 - frontiersin.org
Many complex behaviors in biological systems emerge from large populations of interacting
molecules or cells, generating functions that go beyond the capabilities of the individual …